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Planta Med 2011; 77(16): 1848-1851
DOI: 10.1055/s-0030-1271178
Natural Product Chemistry
Letters
© Georg Thieme Verlag KG Stuttgart · New York

Drimane-Type Sesquiterpenes from Polygonum hydropiper

Rajia Sultana1 , 2 , Rashadul Hossain1 , 2 , Achyut Adhikari2 , Zulfiqar Ali2 , 5 , Sammar Yousuf2 , Muhammad Iqbal Choudhary2 , 3 , Muhammad Yusuff Ali4 , Muhammad Shahed Zaman4
  • 1Department of Chemistry, Chittagong University of Engineering and Technology, Chittagong, Bangladesh
  • 2H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
  • 3Department of Chemistry, King Saud University, Riyadh, Saudi Arabia
  • 4Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
  • 5National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, Mississippi, USA
Further Information

Publication History

received February 26, 2011 revised April 25, 2011

accepted May 9, 2011

Publication Date:
14 June 2011 (online)

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Abstract

One new drimane-type sesquiterpenoid, 3β-angeloyloxy-7-epifutronolide (1), and one new natural product, polygonumate (2), along with six known drimane-type sesquiterpenes [dendocarbin L (3), (+) winterin (4), (+) fuegin (5), changweikangic acid A (6), futronolide (7), and 7-ketoisodrimenin (8)] were isolated from the whole plant of Polygonum hydropiper Linn. Their structures were determined using spectroscopic techniques. Single-crystal X-ray diffraction study on dendocarbin L (3) and 13C-NMR spectroscopic data of (+) winterin (4) are described for the first time. Compound 6 was evaluated for inhibitions of α-chymotrypsin, acetylcholinesterase, and butyrylcholinesterase enzymes.

Key words

Polygonum hydropiper - Polygonaceae - 3β-angeloyloxy-7-epifutronolide - polygonumate - dendocarbin L

Supporting Information

References

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Prof. Muhammad Shahed Zaman

Department of Chemistry
University of Rajshahi

Rajshahi 6205

Bangladesh

Phone: +880 17 16 02 72 11

Fax: +880 7 21 75 00 64

Email: zmshahed@yahoo.com

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