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Pharmacopsychiatry 2016; 49(04): 170-173
DOI: 10.1055/s-0042-104507
DOI: 10.1055/s-0042-104507
Original Paper
Nucleus Accumbens Deep Brain Stimulation for Alcohol Addiction – Safety and Clinical Long-term Results of a Pilot Trial
Further Information
Publication History
received 11 November 2015
revised 25 February 2016
accepted 29 February 2016
Publication Date:
04 May 2016 (online)
Abstract
We report on the long-term clinical outcome (up to 8 years) of 5 patients who received deep brain stimulation (DBS) of the nucleus accumbens to treat their long-lasting and treatment-resistant alcohol addiction. All patients reported a complete absence of craving for alcohol; 2 patients remained abstinent for many years and 3 patients showed a marked reduction of alcohol consumption. No severe or long-standing side effects occurred. Therefore, DBS could be a promising, novel treatment option for severe alcohol addiction, but larger clinical trials are needed to further investigate the efficacy of DBS in addiction.
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