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Synthesis 1987; 1987(10): 857-869
DOI: 10.1055/s-1987-28105
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Synthesis of Natural Products via Isoxazoles

P. G. Baraldi* , A. Barco, S. Benetti, G. P. Pollini, D. Simoni
  • *Dipartimento di Scienze Farmaceutiche, Università di Ferrara, via Scandiana 21, I-44100 Ferrara, Italy
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Publication History

Publication Date:
12 September 2002 (online)

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Synthetic routes to natural products using isoxazole derivatives as key intermediates are reviewed. 1. Introduction 2. General Considerations 2.1. Methods of Preparation 2.2. Functionalization 2.3. Ring Opening Procedures 3. Synthesis of Natural Products via Isoxazole Intermediates 3.1. Isoxazoles as Masked New Heterocyclic Rings 3.2. Isoxazoles as Masked Aromatic Rings 3.3. Isoxazoles as Masked Fused Rings 3.4. Isoxazoles as Masked Aldol and Related Moieties 4. Conclusions

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