Download PDF
Synlett 1993; 1993(3): 226-228
DOI: 10.1055/s-1993-22412
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Enantioselective Synthesis of Protected ß-Amino Acetals and ß-Amino Acids by 1,2-Addition of RM/CeCl3 to 3,3-Ethylenedioxypropanal-SAMP-Hydrazone

Dieter Enders* , Martin Klatt, Rudolf Funk
  • *Institut für Organische Chemie, Rheinisch-Westfälische Technische Hochschule, Professor-Pirlet-Straße 1, D-5100 Aachen, Germany
Further Information

Publication History

Publication Date:
19 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Nucleophilic 1,2-addition of RM/CeCl3 to 3,3-ethylenedioxypropanal-SAMP-hydrazone 2 and subsequent reductive N-N-bond cleavage affords ß-amino acetals 4 in good yields and high enantiomeric excesses, which are easily transformed into ß-amino acids 5

      >