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Synlett 1997; 1997(SI): 457-459
DOI: 10.1055/s-1997-6121
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Asymmetric Synthesis of 1,3-Dialkyl-Substituted Carbon Chains of any Stereochemical Configuration by an Iterable Process

Andrew G. Myers* , Bryant H. Yang, Hou Chen, David J. Kopecky
  • *Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA
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Publication Date:
31 December 2000 (online)

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A highly practical, iterable method for the preparation of 1,3,5,n(odd)-polyalkyl-substituted carbon chains based upon the asymmetric alkylation of pseudoephedrine amide enolates is described.

asymmetric synthesis - pseudoephedrine - enolate - alkylation

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