Minim Invasive Neurosurg 2004; 47(1): 24-28
DOI: 10.1055/s-2003-812537
Original Article
© Georg Thieme Verlag Stuttgart · New York

Cavernous Malformations - Navigational Supported Surgery

D.  Winkler1 , D.  Lindner1 , C.  Trantakis1 , G.  Strauss2 , A.  Richter3 , R.  Schober4 , J.  Meixensberger1
  • 1Department of Neurosurgery, University of Leipzig, Germany
  • 2Department of ENT, University of Leipzig, Germany
  • 3Department of Radiology, University of Leipzig, Germany
  • 4Department of Neuropathology, University of Leipzig, Germany
Further Information

Publication History

Publication Date:
20 April 2004 (online)

Abstract

Objective: Navigational supported surgery of intracranial lesions is expected to be associated with a lower rate of brain traumatization as well as an avoidance of additional neurological deficits and surgical morbidity. In our study we used the computer-assisted image guidance for resection of cerebral cavernous malformations.

Methods: In all patients the planning procedure for the following image-guided surgery was realized using preoperative MRl data sets and a neuronavigation system (STP 4.0, SNN). In cases in which the cavernoma was situated near functional eloquent regions, functional MR images were fused preoperatively.

Results: During the last 24 months, 21 patients were surgically treated for cerebral cavernoma. No patient was operated twice. The mean size of cavernoma was 18.3 mm, ranging from 5 to 60 mm, the mean distance between cortical surface and cavernoma was 26 mm, ranging from 5 to 50 mm. The surgical procedure lasted in the median 180 min. All patients showed an identical or better neurological outcome.

Conclusions: Neuronavigation allows an accurate definition of the intraoperative target, a correct approach and a safe surgery. With the help of neuronavigation the surgical approach and the extirpation of cavernous malformations were realized in a comfortable and safe way and allowed a minimization of tissue manipulation.

References

  • 1 Maesawa S, Kondziolka D, Lunsford D. Stereotactic radiosurgery for management of deep brain cavernous malformations.  Neurosurg Clin N Am. 1999;  10 503-511
  • 2 Meixensberger J, Hoflnann E, Roosen K. Cerebral cavernomas - clinical aspects and therapy.  Wien Med Wochenschr. 1997;  147 194-198
  • 3 Vishteh A G, Nadkarni T, Spetzler R F. Cavernous malformation of the pineal region: short report and review of the literature.  Br J Neurosurg. 2000;  14 147-151
  • 4 Braun V, Antoniadis G, Rath S, Richter H-P. Kavernome.  Nervenarzt. 1996;  67 301-305
  • 5 Zabramski J M, Wascher T M, Spetzler R F, Johnson B, Golfinos J, Drayer B P, Brown B, Rigamonti D, Brown G. The natural history of familial cavernous malformations: results of an ongoing study.  J Neurosurg. 1994;  80 422-432
  • 6 Cohen D S, Lustgarten J H, Miller E, Khandji A G, Goodman R R. Effects of coregistration of MR to CT images on MR stereotactic accuracy.  J Neurosurg. 1995;  82 772-779
  • 7 Dorward N L. Neuronavigation - the surgeon's sextant.  Br J Neurosurg. 1997;  11 101-103
  • 8 Kelly P I. Volumetric stereotactic surgical resection of intra-axial brain mass lesion.  Mayo Clin Proc. 1988;  63 1186-1198
  • 9 Ryan M J, Erickson R K, Levin D N, Pelizzari C A, MacDonald R L, Dohrmann G J. Frameless stereotaxy with real-time tracking of patient head movement and retrospective patient-image registration.  J Neurosurg. 1996;  85 287-292
  • 10 Wirtz C R, Tronnier V M, Bonsanto M M, Habfeld S, Knauth M, Kunze S. Neuronavigation - Methoden und Ausblick.  Nervenarzt. 1998;  69 1029-1036
  • 11 Weil S M, Tew J M. Surgical management of brain stem vascular malformations.  Acta Neurochir (Wien). 1990;  105 14-23
  • 12 Moriarity J L, Clatterbuck R E, Rigamonti D. The natural history of cavernous malformations.  Neurosurg Clin N Am. 1999;  10 411-417
  • 13 Schulder M, Fontana P, Lavenhar M A, Carmel P W. The relationship of imaging techniques to the accuracy of frameless stereotaxy.  Stereotact Funct Neurosurg. 1999;  72 136-141
  • 14 Bertalanffy H, Kuhn G, Scheremet R, Seeger W. Indications for surgery and prognosis in patients with cerebral cavernous angiomas.  Neurol Med Chir. 1992;  32 659-666
  • 15 Zabramski J M, Henn J S, Coons S. Pathology of cerebral vascular malformations.  Neurosurg Clin N Am. 1999;  10 395-410
  • 16 Amin-Hanjani S, Ogilvy C S, Ojemann R G, Crowell R M. Risks of surgical management for cavernous malformations of the nervous system.  Neurosurgery. 1998;  42 1220-1228
  • 17 Awad I A, Robinson J. Cavernous malformation and epilepsy. In: Awad IA, Barrow DL (eds.). Cavernous Malformations. Park Ridge: AANS 1993: 49-63
  • 18 Woydt M, Krone A, Soerensen N, Roosen K. Ultrasound-guided neuronavigation of deep-seated cavernous haemangiomas: clinical results and navigation techniques.  Br J Neurosurg. 2001;  15 485-495
  • 19 Barrow D, Awad I A. Conceptual overview and management strategies. In: Awad lA, Barrow DL (eds.). Cavernous Malformations. Park Ridge: AANS 1993: 205-213
  • 20 Fahlbusch R, Strauss C, Huk W. Pontine-mesencephalic cavernomas: indications for surgery and operative results.  Acta Neurochir Suppl (Wien). 1991;  53 37-41
  • 21 Huhn S, Rigamonti D, Hsu F. Indications for surgical intervention. In Awad IA, Barrow DL (eds.). Cavernous Malformations. Park Ridge: AANS 1993: 87-99
  • 22 Ojemann R G, Crowell R M, Ogilvy C S. Management of cranial and spinal cavernous angiomas.  Clin Neurosurg. 1993;  40 98-123
  • 23 Robinson J R, Awad I A, Little J R. Natural history of the cavernous angioma.  J Neurosurg. 1991;  75 709-714
  • 24 Sakai N, Yamada H, Tanigawara T, Asano Y, Andoh T, Tanabe Y, Takada M. Surgical treatment of cavernous angioma involving the brainstem and review of the literature.  Acta Neurochir (Wien). 1991;  113 138-143
  • 25 Weber M, Vespignani H, Bracard S, Roland J, Picard L, Barroche G, Auque J, Lepoir J. Intracerebral cavernous angioma.  Rev Neurol (Paris) MDN. 1989;  145 429-436
  • 26 Ungersbock K, Aichholzer M, Giinthner M, Rossler K, Gorzer H, Koos W T. Cavernous malformations. From frame-based to frameless stereotactic localization.  Minim Invas Neurosurg. 1997;  40 134-138
  • 27 Matz P, McDermott M, Gutin P, Dillon W, Wilson C. Cavernous malformations: Results of image-guided resection.  J Image Guid Surg. 1995;  1 273-279

Dirk Winkler,M. D. 

Klinik für Neurochirurgie · Universität Leipzig

Johannisallee 34

04103 Leipzig

Germany

Fax: + 49-341-971-2009

Phone: + 49-341-971-2000

Email: wind@server3.medizin.uni-Ieipzig.de

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