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Horm Metab Res 1993; 25(2): 121-124
DOI: 10.1055/s-2007-1002057
Progress in Practical Endocrinology

© Georg Thieme Verlag, Stuttgart · New York

On Line Continuous Monitoring of Subcutaneous Tissue Glucose is Feasible by Combining Portable Glucosensor with Microdialysis

E. F. Pfeiffer1 , C. Meyerhoff1 , Friederike Bischof1 , F. S. Keck2 , W. Kerner3
  • 1Institut für Diabetes Technologie an der Universität Ulm, Ulm
  • 2Abt. Innere Medizin I, Medizinische Klinik und Poliklinik der Universität Ulm, Ulm
  • 3Klinik für Innere Medizin, Medizinische Universität zu Lübeck, Lübeck, Germany
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Publication History

1992

1992

Publication Date:
14 March 2008 (online)

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Summary

A new method for continuous measurement of subcutaneous tissue glucose content is introduced: by combining the microdialysis technique with a wearable amperometric glucose sensor, a device for continuous glucose measurement in the subcutaneous tissue was obtained. This device was applied to healthy volunteers (n = 10) over the period of an oral glucose load and to type I diabetic patients (n = 10) under the conditions of daily life. Glucose profiles in both healthy and diabetic persons were followed in the subcutaneous tissue up to 27 hours. This technique will certainly open new perspectives of monitoring and treating diabetic patients.

Key words

Subcutaneous Tissue Glucose - Glucose Sensor - Microdialysis

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