Register      Login
Microbiology Australia Microbiology Australia Society
Microbiology Australia, bringing Microbiologists together
RESEARCH ARTICLE

The malaria war

Aya C Taki A and Peter M Smooker A
+ Author Affiliations
- Author Affiliations

Biotechnology and Biological Sciences Discipline
School of Applied Sciences
RMIT University
PO Box 71
Bundoora, Vic. 3083, Australia
Tel: +61 3 9925 7129
Fax: +61 3 9925 7110
Email: aya.taki@rmit.edu.au
Email: peter.smooker@rmit.edu.au

Microbiology Australia 35(3) 153-155 https://doi.org/10.1071/MA14046
Published: 26 August 2014

Abstract

The 25th of April is a national day to honour the members of the Australian and New Zealand Army Corps (ANZAC), who gave their lives at Gallipoli during the First World War (WWI). The 25th of April has also been designated World Malaria Day by the World Health Organization (WHO), and is commemorated every year to bring awareness of deaths caused by malaria infection and global efforts to control infection. There is no coincidence that these two commemorative events are on the same day, as military campaigns suffered great burdens caused by malaria infection during WWI. Malaria infection is yet to be eradicated from human history; fundamental discoveries of malaria and its control were developed during WWI and the fight against malaria continues to this date. This article focuses on the discovery of malaria prior to WWI, the impact that malaria had on military in the war, and the development of control measures taken to minimize these effects and to subsequently eradicate the disease in many countries.


References

[1]  Singh, B. et al. (2004) A large focus of naturally acquired Plasmodium knowlesi infections in human beings. Lancet 363, 1017–1024.
A large focus of naturally acquired Plasmodium knowlesi infections in human beings.Crossref | GoogleScholarGoogle Scholar | 15051281PubMed |

[2]  World Health Organization (2014) WHO | Malaria. WHO Fact Sheet .

[3]  Idro, R. et al. (2010) Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome. Pediatr. Res. 68, 267–274.
Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome.Crossref | GoogleScholarGoogle Scholar | 20606600PubMed |

[4]  Payne, D. (2008) Malaria in the Great War. The Western Front Association.

[5]  Cox, F.E. (2010) History of the discovery of the malaria parasites and their vectors. Parasit Vectors

[6]  Haas, L.F. (1999) Charles Louis Alphonse Laveran (1845–1922). J. Neurol. Neurosurg. Psychiatry 67, 520.
Charles Louis Alphonse Laveran (1845–1922).Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK1MvhslOmtA%3D%3D&md5=007da2b374439b13ad32b717e348e3c0CAS | 10486402PubMed |

[7]  Ross, R. (1897) On some peculiar pigmented cells found in two mosquitos fed on malarial blood. BMJ 2, 1786–1788.
On some peculiar pigmented cells found in two mosquitos fed on malarial blood.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC3MzhvVOlsg%3D%3D&md5=640d7c924058e1a0627c3dca2e7954e5CAS | 20757493PubMed |

[8]  Agyepong, I.A. (1992) Malaria: Ethnomedical perceptions and practice in an Adangbe farming community and implications for control. Soc. Sci. Med. 35, 131–137.
Malaria: Ethnomedical perceptions and practice in an Adangbe farming community and implications for control.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK38zns1KjtQ%3D%3D&md5=673fd842dd8763474bc75710328a049dCAS | 1509302PubMed |

[9]  Kitchen, L.W. et al. (2006) Reviews of anti‐infective agents: Role of US military research programs in the development of US food and drug administration–approved antimalarial drugs. Clin. Infect. Dis. 43, 67–71.
Reviews of anti‐infective agents: Role of US military research programs in the development of US food and drug administration–approved antimalarial drugs.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28XntV2ks70%3D&md5=73e8bdbc60732af7aa2925cb58da7efcCAS | 16758420PubMed |

[10]  Guttmann, P. and Ehrlich, P. (1891) Über die Wirkung des Methylenblau bei Malaria (On the effect of methylene blue on malaria) Berliner Klinische Wochenschrift 28, 953–956.

[11]  Krafts, K. et al. (2012) From methylene blue to chloroquine: a brief review of the development of an antimalarial therapy. Parasitol. Res. 111, 1–6.
From methylene blue to chloroquine: a brief review of the development of an antimalarial therapy.Crossref | GoogleScholarGoogle Scholar | 22411634PubMed |

[12]  Kamarck, A.M. (1976) Tropics and economic development: a provocative view into the poverty of nations, Johns Hopkins University.

[13]  Majori, G. (2012) Short history of malaria and its eradication in Italy with short notes on the fight against the infection in the Mediterranean basin. Mediterr. J. Hematol. Infec. Dis. 4, 1.
Short history of malaria and its eradication in Italy with short notes on the fight against the infection in the Mediterranean basin.Crossref | GoogleScholarGoogle Scholar |

[14]  Breman, J.G. (2001) The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. Am. J. Trop. Med. Hyg. 64, 1–11.
| 1:STN:280:DC%2BD3MzmsVKquw%3D%3D&md5=ee32661be8e90593ef2f5de8da89aa45CAS | 11425172PubMed |

[15]  Bruce-Chwatt, L.J. and de Zulueta, J. (1980) The rise and fall of malaria in Europe, Oxford University Press on behalf of the Regional Office for Europe of the World Health Organization.

[16]  Greenwood, B.M. et al. (2008) Malaria: progress, perils, and prospects for eradication. J. Clin. Invest. 118, 1266–1276.
Malaria: progress, perils, and prospects for eradication.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXkt1CntLg%3D&md5=9b1c58c583f44c71bdeb64c05d1f6e38CAS | 18382739PubMed |

[17]  Nájera, J.A. et al. (2011) Some lessons for the future from the Global Malaria Eradication Programme (1955–1969). PLoS Med. 8, e1000412.
Some lessons for the future from the Global Malaria Eradication Programme (1955–1969).Crossref | GoogleScholarGoogle Scholar | 21311585PubMed |

[18]  Sidhu, A.B.S. (2002) Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science 298, 210–213.
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38XnsFSgs70%3D&md5=a13ecc1a8c75b3b7090b48d3aa198b0bCAS |

[19]  Coetzee, M. and Koekemoer, L.L. (2013) Molecular systematics and insecticide resistance in the major African malaria vector Anopheles funestus. Annu. Rev. Entomol. 58, 393–412.
Molecular systematics and insecticide resistance in the major African malaria vector Anopheles funestus.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3sXivVWjtL8%3D&md5=79682b0b94dba73693cf733c45c16890CAS | 23317045PubMed |

[20]  Regules, J.A. et al. (2011) The RTS,S vaccine candidate for malaria. Expert Rev. Vaccines 10, 589–599.
The RTS,S vaccine candidate for malaria.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXmsFymu7o%3D&md5=99b82a02d24b9fcec1578f7f5dedb2b0CAS | 21604980PubMed |

[21]  Bejon, P. et al. (2013) Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data. Lancet Infect. Dis. 13, 319–327.
Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3sXjslWqs7Y%3D&md5=9b61c0c3960d65eed58ca4ee831284cbCAS | 23454164PubMed |