Journal of Biological Chemistry
Volume 287, Issue 16, 13 April 2012, Pages 13228-13238
Molecular Bases of DiseaseCharacterization of EHop-016, Novel Small Molecule Inhibitor of Rac GTPase*
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open access
Actin
Cdc42
Enzyme Inhibitors
GTPase
Guanine Nucleotide Exchange Factor (GEF)
Rac
Rho
Rho GTPases
Rac Inhibitor, Ehop-016, Rac GEFs
Cited by (0)
- *
This work was supported, in whole or in part, by National Institutes of Health, NCRR, Grants G12RR035051 (to the University of Puerto Rico Medical Sciences Campus), 5U54CA096297 (to the University of Puerto Rico Medical Sciences Campus), and G12RR03035 (to Universidad Central del Caribe). This work was also supported by Department of Defense/United States Army Breast Cancer Research Program Grants W81XWH-07-1-0330 and 3SC3GM084824-02S1 (to S. D.). A provisional patent application, number 61/536,069, “Novel Small-Molecule Inhibitors of Rac 1 in Metastatic Breast Cancer,” is pending.
This article contains supplemental Figs. S1–S3.
- 1
Both authors contributed equally to this work.
© 2012 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.