Journal of Biological Chemistry
Volume 285, Issue 41, 8 October 2010, Pages 31731-31741
Protein Structure and FoldingNovel Zn2+-binding Sites in Human Transthyretin: IMPLICATIONS FOR AMYLOIDOGENESIS AND RETINOL-BINDING PROTEIN RECOGNITION*
Under a Creative Commons license
open access
Amyloid
NMR
Vitamin A
X-ray Crystallography
Zinc
Retinol-binding Protein
Transthyretin
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The atomic coordinates and structure factors (codes 3GRG, 3GRB, 3GPS, and 3DGD) have been deposited in the Protein Data Bank, Research Collaboratory for Structural Bioinformatics, Rutgers University, New Brunswick, NJ (http://www.rcsb.org/).
- *
This work was supported by CNPq (INCT-Bioimagem e Biologia Estrutural), CAPES Nanobiotec-Brasil 04-2008, and FAPERJ (to D. F. and L. M. T. R. L.).
The on-line version of this article (available at http://www.jbc.org) contains supplemental Tables S1 and S2 and Figs. S1–S6.
- 1
Both authors contributed equally to this work.
- 2
Supported by a fellowship from CNPq, CAPES PNPD-2009, and FAPERJ.
© 2010 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.