Journal of Biological Chemistry
MetabolismDisruption of the Sjögren-Larsson Syndrome Gene Aldh3a2 in Mice Increases Keratinocyte Growth and Retards Skin Barrier RecoveryDisruption of Aldh3a2 Gene
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This work was supported by Advanced Research and Development Programs for Medical Innovation (AMED-CREST) (to A. K.) from the Japan Agency for Medical Research and Development (AMED), by Grant-in-Aid for Scientific Research (A) 26251010 (to A. K.) from the Japan Society for the Promotion of Science (JSPS), and by Grant-in-aid for JSPS Fellows 25744 (to T. N.) from JSPS. The authors declare that they have no conflicts of interest with the contents of this article.
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The abbreviations used are:
- SLS
Sjögren-Larsson syndrome
- FALDH
fatty aldehyde dehydrogenase
- MC
medium-chain
- LC
long-chain
- FA
fatty acid
- LCB
long-chain base
- EOS
esterified ω-hydroxyacylsphingosine
- DHS
dihydrosphingosine
- ALDH
aldehyde dehydrogenase
- TEWL
transepidermal water loss
- PC
phosphatidylcholine
- PE
phosphatidylethanolamine
- PlsC
plasmanyl/plasmenylcholine
- PlsE
plasmanyl/plasmenylethanolamine
- d7
deuterium.