Journal of Biological Chemistry
Volume 291, Issue 43, 21 October 2016, Pages 22618-22629
Molecular Bases of DiseaseSmall Heat-shock Proteins Prevent α-Synuclein Aggregation via Transient Interactions and Their Efficacy Is Affected by the Rate of Aggregation*
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open access
α-synuclein (a-synuclein)
amyloid
analytical ultracentrifugation
fibril
molecular chaperone
Parkinson disease
protein aggregation
small heat shock protein (sHsp)
synuclein
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- *
This work was supported in part by grants from the Australian Department of Health and Aging and the University of Wollongong. The authors declare that they have no conflicts of interest with the contents of this article.
- 1
Supported by an Australian Postgraduate Award.
- 2
Supported by Australian Research Council Future Fellowships FT110100586 and FT140100544.
- 3
Supported by an Australian National Health and Medical Research Council project Grant 1068087.
© 2016 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.