Journal of Biological Chemistry
Volume 293, Issue 29, 20 July 2018, Pages 11415-11423
Signal TransductionEpigenetic and transcriptional regulation of IL4-induced CCL17 production in human monocytes and murine macrophages
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interferon regulatory factor (IRF)
STAT transcription factor
signal transduction
epigenetics
monocyte
macrophage
chemokine
cytokine
dendritic cell
interleukin
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This work was supported by grants from the National Health and Medical Research Council of Australia (to J. A. H. and A. D. C), and a Research Grant Support Scheme from the University of Melbourne (to A. A.). The authors declare that they have no conflicts of interest with the contents of this article.
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The abbreviations used are:
- IL4
interleukin 4
- IRF4
interferon regulatory factor 4
- GM-CSF
granulocyte macrophage-colony-stimulating factor
- BMM
bone marrow–derived macrophages
- TSS
transcription start site
- STAT6
signal transducer and activator of transcription 6
- JMJD3
jumonji domain–containing protein 3
- KDM6B
lysine-specific demethylase 6B
- qPCR
quantitative PCR
- HPRT
hypoxanthine-guanine phosphoribosyltransferase
- Ab
antibody
- ANOVA
analysis of variance.
© 2018 Hsu et al.