Journal of Biological Chemistry
Volume 294, Issue 32, 9 August 2019, Pages 11994-12006
Cell BiologyInterferon-γ induces the cell surface exposure of phosphatidylserine by activating the protein MLKL in the absence of caspase-8 activityIFN-γ induces phosphatidylserine exposure
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caspase
cell death
interferon
necrosis (necrotic death)
phosphatidylserine
receptor-interacting protein (RIP)
interferon-gamma
MLKL
necroptosis
RIPK3
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1 This work was supported by Grant-in-Aid for Scientific Research on Innovative Areas (homeostatic regulation by various types of cell death) from the Ministry of Education, Culture, Sports, Science and Technology of Japan (15H01376 to S. Y.). The authors declare that they have no conflicts of interest with the contents of this article.
This article contains Figs. S1–S11.
© 2019 Chen et al.