Journal of Biological Chemistry
Volume 290, Issue 33, 14 August 2015, Pages 20527-20540
Protein Structure and FoldingThe Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers*
Under a Creative Commons license
open access
α-synuclein (a-synuclein)
neurodegeneration
neurotrophic factor
Parkinson disease
protein dynamic
protein structure
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The atomic coordinates and structure factors (code 4BIT) have been deposited in the Protein Data Bank (http://wwpdb.org/).
The 1H, 13C, and 15N chemical shifts of CDNF have been deposited in the BioMagResBank (71) under BMRB code 19164.
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This work was supported by Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro and Conselho Nacional de Desenvolvimento Científico e Tecnológico Grants Universal 470349/2012-3, APQ1/E-26/111.771/2012 (to M. S. A.) and Universal 442991/2014-2, APQ1/E-26/111.415/2013 (to F. L. P.). The authors declare that they have no conflicts of interest with the contents of this article.
© 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.