Molecular & Cellular Proteomics
ResearchThe Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis* [S]
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* This work was supported by the Biotechnology and Biological Sciences Research Council, grant BB/L019612/1 (to M.W.R) and the European Research Council, grant 2012 AdG (to J.P.D).
Author contributions: A.M., J.P.D., and M.W.R. designed research; K.C., E.d., M.T., D.B., P.J.D., G.P.B., A.M., and M.W.R. performed research; K.C., M.T., D.B., P.J.D., G.P.B., S.O., J.T., S.P., A.M., J.P.D., and M.W.R. contributed new reagents or analytic tools; K.C., E.d., M.T., D.B., P.J.D., S.P., A.M., J.P.D., and M.W.R. analyzed data; K.C., E.d., J.P.D., and M.W.R. wrote the paper.
Data access statement: Genomic and transcriptomic data are available from the European Nucleotide Archive under the accession numbers PRJEB6687 and PRJEB6904 respectively. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the data set identifier PXD002570.
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This article contains supplemental Figs. S1, S2 and Tables S1 to S4.
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These authors contributed equally.