Near-field diffraction tomography with diffuse photon density waves

Xingde Li, Deva N. Pattanayak, Turgut Durduran, Joseph P. Culver, Britton Chance, and Arjun G. Yodh
Phys. Rev. E 61, 4295 – Published 1 April 2000
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Abstract

An angular spectrum algorithm is presented for fast, near-field diffraction tomographic imaging with diffuse photon density waves in highly scattering media. A general relation in K space is derived that connects the spatial variations of the optical properties of heterogeneities to the spatial spectra of the measured scattered diffuse photon density waves. The theory is verified experimentally for situations when boundary effects can be neglected. We further describe how to reconstruct absorption and scattering properties simultaneously, and how to incorporate boundary conditions into this angular spectrum algorithm for a turbid medium of finite size (e.g., the slab medium). Limitations and potential improvements of the near-field diffraction tomography are also discussed.

  • Received 20 August 1999

DOI:https://doi.org/10.1103/PhysRevE.61.4295

©2000 American Physical Society

Authors & Affiliations

Xingde Li1,2,*, Deva N. Pattanayak2,3, Turgut Durduran1, Joseph P. Culver1, Britton Chance2, and Arjun G. Yodh1

  • 1Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104
  • 2Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104
  • 3Silicon Power Corporation, 3 Northway Lane North, Latham, New York 12110

  • *Present address: Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139. Electronic address: xingde@mit.edu

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Vol. 61, Iss. 4 — April 2000

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