Lévy scaling: The diffusion entropy analysis applied to DNA sequences

Nicola Scafetta, Vito Latora, and Paolo Grigolini
Phys. Rev. E 66, 031906 – Published 20 September 2002
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Abstract

We address the problem of the statistical analysis of a time series generated by complex dynamics with the diffusion entropy analysis (DEA) [N. Scafetta, P. Hamilton, and P. Grigolini, Fractals 9, 193 (2001)]. This method is based on the evaluation of the Shannon entropy of the diffusion process generated by the time series imagined as a physical source of fluctuations, rather than on the measurement of the variance of this diffusion process, as done with the traditional methods. We compare the DEA to the traditional methods of scaling detection and prove that the DEA is the only method that always yields the correct scaling value, if the scaling condition applies. Furthermore, DEA detects the real scaling of a time series without requiring any form of detrending. We show that the joint use of DEA and variance method allows to assess whether a time series is characterized by Lévy or Gauss statistics. We apply the DEA to the study of DNA sequences and prove that their large-time scales are characterized by Lévy statistics, regardless of whether they are coding or noncoding sequences. We show that the DEA is a reliable technique and, at the same time, we use it to confirm the validity of the dynamic approach to the DNA sequences, proposed in earlier work.

  • Received 9 January 2002

DOI:https://doi.org/10.1103/PhysRevE.66.031906

©2002 American Physical Society

Authors & Affiliations

Nicola Scafetta1,2, Vito Latora3, and Paolo Grigolini2,4,5

  • 1Pratt School EE Department, Duke University, P.O. Box 90291, Durham, North Carolina 27708
  • 2Center for Nonlinear Science, University of North Texas, P.O. Box 311427, Denton, Texas 76203-1427
  • 3Dipartimento di Fisica e Astronomia, Università di Catania and INFN, Corso Italia 57, 95129 Catania, Italy
  • 4Dipartimento di Fisica dell’Università di Pisa and INFM, Piazza Torricelli 2, 56127 Pisa, Italy
  • 5Istituto di Biofisica CNR, Area della Ricerca di Pisa, Via Alfieri 1, San Cataldo 56010 Ghezzano-Pisa, Italy

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Issue

Vol. 66, Iss. 3 — September 2002

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