Abstract
Biomolecular systems like molecular motors or pumps, transcription and translation machinery, and other enzymatic reactions, can be described as Markov processes on a suitable network. We show quite generally that, in a steady state, the dispersion of observables, like the number of consumed or produced molecules or the number of steps of a motor, is constrained by the thermodynamic cost of generating it. An uncertainty requires at least a cost of independent of the time required to generate the output.
- Received 29 October 2014
DOI:https://doi.org/10.1103/PhysRevLett.114.158101
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