Hostname: page-component-8448b6f56d-sxzjt Total loading time: 0 Render date: 2024-04-19T08:40:01.595Z Has data issue: false hasContentIssue false
  • English
  • Français

Oxidative biology: new intervention opportunities in psychiatry

Published online by Cambridge University Press:  24 June 2014

Michael Berk
Michael Berk*
Affiliation:
Department of Clinical and Biomedical Sciences: Barwon Health, University of Melbourne, Geelong, Victoria, Australia ORYGEN Youth Health, Melbourne, Victoria, Australia Mental Health Research Institute, Melbourne, Victoria, Australia
*
Professor Michael Berk, Department of Clinical and Biomedical Sciences, Swanston Centre – Barwon Health, University of Melbourne, PO Box 281, Geelong, VIC 3220, Australia Tel: +61 3 5226 7450; Fax: +61 3 5246 5165; E-mail: mikebe@barwonhealth.org.au
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Intervention Insights
Information
Acta Neuropsychiatrica , Volume 19 , Issue 4 , August 2007 , pp. 259 - 260
Copyright
Copyright © 2007 Blackwell Munksgaard

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Looney, JM, Childs, HM. The lactic acid and glutathione content of the blood of schizophrenic patients. J Clin Invest 1934;13:963–968. CrossRefGoogle ScholarPubMed
Yao, JK, Leonard, S, Reddy, R. Altered glutathione redox state in schizophrenia. Dis Markers 2006;22:83–93. CrossRefGoogle Scholar
Reddy, R, Keshavan, M, Yao, JK. Reduced plasma antioxidants in first-episode patients with schizophrenia. Schizophr Res 2003;62:205–212. CrossRefGoogle ScholarPubMed
Kuloglu, M, Ustundag, B, Atmaca, Met al. Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder. Cell Biochem Funct 2002;20:171–175. CrossRefGoogle ScholarPubMed
Ozcan, ME, Gulec, M, Ozerol, E, Polat, R, Akyol, O. Antioxidant enzyme activities and oxidative stress in affective disorders. Int Clin Psychopharmacol 2004;19:89–95. CrossRefGoogle ScholarPubMed
James, SJ, Cutler, P, Melnyk, Set al. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr 2004;80:1611–1617. Google ScholarPubMed
Zoroglu, SS, Armutcu, F, Ozen, Set al. Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism. Eur Arch Psychiatry Clin Neurosci 2004;254:143–147. CrossRefGoogle ScholarPubMed
Chauhan, A, Chauhan, V, Brown, WT, Cohen, I. Oxidative stress in autism: increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferring – the antioxidant proteins. Life Sci 2004;75:2539–2549. CrossRefGoogle Scholar
Sogut, S, Zoroglu, SS, Ozyurt, Het al. Changes in nitric oxide levels and antioxidant enzyme activities may have a role in the pathophysiological mechanisms involved in autism. Clin Chim Acta 2003;331:111–117. CrossRefGoogle ScholarPubMed
Bilici, M, Efe, H, Koroglu, MAet al. Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments. J Affect Disord 2001;64:43–51. CrossRefGoogle ScholarPubMed
Harada, S, Tachikawa, H, Kawanishi, Y. Glutathione S-transferase M1 gene deletion may be associated with susceptibility to certain forms of schizophrenia. Biochem Biophys Res Commun 2001;281:267–271. CrossRefGoogle ScholarPubMed
Parikh, V, Khan, MM, Mahadik, SP. Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. J Psychiatr Res 2003;37:43–51. CrossRefGoogle ScholarPubMed
Shao, L, Young, LT, Wang, JF. Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells. Biol Psychiatry 2005;58:879–884. CrossRefGoogle ScholarPubMed
Do, KQ, Trabensinger, MK, Lauer, CJet al. Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo. Eur J Neurosci 2000;12:3721–3728. CrossRefGoogle ScholarPubMed
Reddy, RD, Yao, JK. Free radical pathology in schizophrenia: a review. Prostaglandins Leukot Essent Fatty Acids 1996;55:33–43. CrossRefGoogle ScholarPubMed
Larowe, SD, Mardikian, P, Malcolm, Ret al. Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals. Am J Addict 2006;15:105–110. CrossRefGoogle ScholarPubMed