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Comparative Study of Magnetic Resonance Imaging and Image-Based Computational Fluid Dynamics for Quantification of Pulsatile Flow in a Carotid Bifurcation Phantom

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Abstract

A combined magnetic resonance imaging (MRI) and computational fluid dynamics (CFD) modeling study was carried out for pulsatile flow in a carotid bifurcation phantom. The aim of the study was to quantify differences in flow patterns between MRI measurement and MRI-based CFD simulations and to further explore the potential for in vivo applications. The computational model was reconstructed from high resolution magnetic resonance (MR) scans. Velocities derived from phase-contrast MR measurements were used as boundary conditions for the CFD calculation. Detailed comparisons of velocity patterns were made between the CFD results and MRI measurements. Good agreement was achieved for the main velocity component in both well-behaved flow (in the common carotid) and disturbed region (in the carotid sinus). Comparison of in-plane velocity vectors showed less satisfactory consistency and revealed that the MR measurements obtained were inadequate to depict the secondary flow pattern as expected. It can be concluded that the combined MRI/CFD is expected to provide more reliable information about the full three-dimensional velocity field. © 2003 Biomedical Engineering Society.

PAC2003: 8761Lh, 8719Uv, 8385Pt, 8710+e

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Authors and Affiliations

  1. Department of Chemical Engineering and Chemical Technology, Imperial College, London, United Kingdom

    S. Z. Zhao & X. Y. Xu

  2. Medical Physics, Department of Medical and Radiological Sciences, Edinburgh University, Edinburgh, United Kingdom

    P. Papathanasopoulou & I. Marshall

  3. Brunel Institute for Bioengineering, Brunel University, Middlesex, United Kingdom

    Q. Long

Authors
  1. S. Z. Zhao
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  2. P. Papathanasopoulou
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  3. Q. Long
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  4. I. Marshall
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  5. X. Y. Xu
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Zhao, S.Z., Papathanasopoulou, P., Long, Q. et al. Comparative Study of Magnetic Resonance Imaging and Image-Based Computational Fluid Dynamics for Quantification of Pulsatile Flow in a Carotid Bifurcation Phantom. Annals of Biomedical Engineering 31, 962–971 (2003). https://doi.org/10.1114/1.1590664

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