Bone vascularization: a way to study bone microarchitecture?

P. Blery; F. Autrusseau; E. Crauste; Erwan Freuchet; Pierre Weiss; J.-P. Guédon; Y. Amouriq

doi:10.1117/12.2042791

13 March 2014 Bone vascularization: a way to study bone microarchitecture?

P. Blery, F. Autrusseau, E. Crauste, Erwan Freuchet, Pierre Weiss, J.-P. Guédon, Y. Amouriq

Proceedings Volume 9038, Medical Imaging 2014: Biomedical Applications in Molecular, Structural, and Functional Imaging; 903812 (2014) https://doi.org/10.1117/12.2042791
Event: SPIE Medical Imaging, 2014, San Diego, California, United States

Abstract

Trabecular bone and its microarchitecture are of prime importance for health. Studying vascularization helps to better know the relationship between bone and vascular microarchitecture. This research is an animal study (nine Lewis rats), based on the perfusion of vascularization by a contrast agent (a mixture of 50% barium sulfate with 1.5% of gelatin) before euthanasia. The samples were studied by micro CT at a resolution of 9μm. Softwares were used to show 3D volumes of bone and vessels, to calculate bone and vessels microarchitecture parameters. This study aims to understand simultaneously the bone microarchitecture and its vascular microarchitecture.

Citation Download Citation

P. Blery, F. Autrusseau, E. Crauste, Erwan Freuchet, Pierre Weiss, J.-P. Guédon, and Y. Amouriq "Bone vascularization: a way to study bone microarchitecture?", Proc. SPIE 9038, Medical Imaging 2014: Biomedical Applications in Molecular, Structural, and Functional Imaging, 903812 (13 March 2014); https://doi.org/10.1117/12.2042791

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