Simultaneous optical and mechanical probes to investigate complex cellular responses to physical cues

Kristina Haase; Zeinab Al-Rekabi; Louise Guolla; Ryan Hickey; Dominique Tremblay; Andrew E. Pelling

doi:10.1117/12.2078336

6 March 2015 Simultaneous optical and mechanical probes to investigate complex cellular responses to physical cues

Kristina Haase, Zeinab Al-Rekabi, Louise Guolla, Ryan Hickey, Dominique Tremblay, Andrew E. Pelling

Proceedings Volume 9327, Optical Elastography and Tissue Biomechanics II; 93270I (2015) https://doi.org/10.1117/12.2078336
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Living cells possess an exquisite ability to sense and respond to physical information in their microenvironment. This ability plays a key role in many fundamentally important physiological and pathological processes. We will describe our work utilizing a variety of biophysical tools to investigate the dynamic responses of cells to mechanical stimuli and how physical cues can be employed to re-purpose and manipulate biological processes. These responses to physical cues are not simply a side-product of biology but are key components of biological and physical feedback loops that govern the life of a cell.

Citation Download Citation

Kristina Haase, Zeinab Al-Rekabi, Louise Guolla, Ryan Hickey, Dominique Tremblay, and Andrew E. Pelling "Simultaneous optical and mechanical probes to investigate complex cellular responses to physical cues", Proc. SPIE 9327, Optical Elastography and Tissue Biomechanics II, 93270I (6 March 2015); https://doi.org/10.1117/12.2078336

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