Comparison of the extent of Nd:YAG and diode (810 nm) laser-induced thermal coagulation of human prostate: a histopathological analysis of acute response

Eduardo Orihuela M.D.; Mariela Pow-Sang M.D.; Steve Johnson M.D.; Daniel Cowan M.D.; Michael M. Warren M.D.; Massoud Motamedi

doi:10.1117/12.209083

12 May 1995 Comparison of the extent of Nd:YAG and diode (810 nm) laser-induced thermal coagulation of human prostate: a histopathological analysis of acute response

Eduardo Orihuela M.D., Mariela Pow-Sang M.D., Steve Johnson M.D., Daniel Cowan M.D., Michael M. Warren M.D., Massoud Motamedi

Author Affiliations +

Proceedings Volume 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V; (1995) https://doi.org/10.1117/12.209083
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

The objective of the study was to compare the extent of thermocoagulation induced in the human prostate by two regimens of Nd:YAG laser (50 W X 60 s and 15 W X 180 s) and one regimen of diode (810 nm) laser (15 W X 180 s). Powers were measured at the fiber tip. The study was conducted in 6 patients undergoing radical prostatectomy because of malignancy whose prostates were treated transurethrally with laser radiation at the time of the procedure. The prostate specimens were retrieved approximately 90 minutes after laser treatment, and then prepared for histological examination. In all the cases, the diode laser was applied to the left side of the prostate and the Nd:YAG laser (either regimen) to the right side, in order to prevent treatment variables related to histological composition. Coagulation necrosis was confined within the transition zone in all the case and at times BPH was unaffected, if nodular. Similar depth of coagulation was observed for both Nd:YAG regimens (mean 12 mm, range 10 to 14) and the depth of coagulation was slightly less for the diode laser (mean 10.6 mm, range 8 to 14). Our results suggest that, at the studied dosimetries, the thermocoagulation effect of diode laser in the human prostate approximates to that seen with Nd:YAG laser.

Citation Download Citation

Eduardo Orihuela M.D., Mariela Pow-Sang M.D., Steve Johnson M.D., Daniel Cowan M.D., Michael M. Warren M.D., and Massoud Motamedi "Comparison of the extent of Nd:YAG and diode (810 nm) laser-induced thermal coagulation of human prostate: a histopathological analysis of acute response", Proc. SPIE 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V, (12 May 1995); https://doi.org/10.1117/12.209083

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available