Getting a-breast of immobilisation needs for the implementation of phase contrast tomography

Sarah J. Lewis; Nathan Tam; Lucia Mariel Arana Pena; Isabella Juria; Seyedamir Tavakoli Taba; Daniel Hausermann; Patrick C. Brennan; Chris Hall; Benedicta Arhatari; Giuliana Tromba; Renata Longo; Timur E. Gureyev

doi:10.1117/12.2563572

22 May 2020 Getting a-breast of immobilisation needs for the implementation of phase contrast tomography

Sarah J. Lewis, Nathan Tam, Lucia Mariel Arana Pena, Isabella Juria, Seyedamir Tavakoli Taba, Daniel Hausermann, Patrick C. Brennan, Chris Hall, Benedicta Arhatari, Giuliana Tromba, Renata Longo, Timur E. Gureyev

Author Affiliations +

Proceedings Volume 11513, 15th International Workshop on Breast Imaging (IWBI2020); 115131P (2020) https://doi.org/10.1117/12.2563572
Event: Fifteenth International Workshop on Breast Imaging, 2020, Leuven, Belgium

Abstract

Aim: In recent years Phase Contrast Tomography (PCT) has been rapidly progressing towards clinical translation as an advanced imaging technology for breast cancer diagnosis. Recent optimization of PCT with mastectomy samples has refined imaging protocols and biomedical-engineering prowess is now required to formalize patient table and breast immobilisation requirements. PCT imaging requires women to lie in prone position similar to conventional breast CT, however the imaging couch rotates above the beam allowing exposure of the breast beneath. Motion artefact through involuntary movement of the breast through the rotation cycle has the potential to reduce diagnostic quality of the results. Methods: This paper details the biomedical engineering cycle of breast holder development alongside medical physics considerations. Breast immobilisation via a plastic or silicone supporting material which is sufficiently transparent for X-rays in the targeted energy range is explained, including the two step process of considering single cup versus double cup solutions and how mild-suction to the breast can be implemented in order to maximum breast tissue visualization and assist with dose uniformity. Results: Considering patient comfort, breast positioning and implications upon attenuation and phase shift, a number of models were developed in Australia and Italy. Early prototypes are described here with some preliminary imaging. Considerable work is taking place over the next three months as models undergo imaging with mastectomy samples at the Imaging and Medical Beamline at the Australian Synchrotron and the ELETTRA Synchrotron Italy. Consumer representatives will be rating the immobilisation device for comfort prior to the start of clinical trials in 2020.

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Sarah J. Lewis, Nathan Tam, Lucia Mariel Arana Pena, Isabella Juria, Seyedamir Tavakoli Taba, Daniel Hausermann, Patrick C. Brennan, Chris Hall, Benedicta Arhatari, Giuliana Tromba, Renata Longo, and Timur E. Gureyev "Getting a-breast of immobilisation needs for the implementation of phase contrast tomography", Proc. SPIE 11513, 15th International Workshop on Breast Imaging (IWBI2020), 115131P (22 May 2020); https://doi.org/10.1117/12.2563572

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