1994 Volume 36 Issue 4 Pages 788-792_1
A 47-year-old female suffered from erosions in the oral cavity and bullae on the skin of trunk. A diagnosis of pemphigus vulgaris was made by the histological findings and direct immunof luorescence examinations of the bulla. Erythema nodosum was also found on the lower legs. In the course of pemphigus vulgaris, she sufferd from diarrhea and stool occult blood examinations continued to be positive. Barium enema examination and colonoscopy were performed and the diagnosis of ulcerative colitis was confirmed. Autoimmune mechanism has been involved in the pathogenesis of pemphigus vulgaris. Ulcerative colitis is also considered to have some autoimmune aspects. We have reported a rare case of ulcerative dolitis associated with pemphigus vulgaris and erythema nodosum.
