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Aspergillus ochraceus micromycetes—producers of extracellular proteinases—protein C activators of blood plasma

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Abstract

Natural isolates of Aspergillus ochraceus micromycetes from soil and plant remains from various regions have been screened. The isolated strains were characterized by similar cultural and morphological features and an identical nucleotide sequence in the ITS1-5,8S-ITS2 region of rDNA. The ability of the extracellular proteinases of A. ochraceus micromycetes to activate protein C of blood plasma has been established. Differences are revealed in the accumulation of proteinases activating protein C and proteinases with thrombinand plasmin-like activities in the growth dynamics of producers.

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Authors and Affiliations

  1. Biological Faculty, Moscow State University, Moscow, 119991, Russia

    A. A. Osmolovskiy, V. G. Kreier, A. V. Kurakov & N. . Baranova

  2. International Biotechnological Center, Moscow State University, Moscow, 119991, Russia

    N. S. Egorov

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  1. A. A. Osmolovskiy
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  2. V. G. Kreier
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  3. A. V. Kurakov
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  4. N. . Baranova
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  5. N. S. Egorov
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Correspondence to A. A. Osmolovskiy.

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Original Russian Text © A.A. Osmolovskiy, V.G. Kreier, A.V. Kurakov, N.A. Baranova, N.S. Egorov, 2012, published in Prikladnaya Biokhimiya i Mikrobiologiya, 2012, Vol. 48, No. 5, pp. 537–542.

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Osmolovskiy, A.A., Kreier, V.G., Kurakov, A.V. et al. Aspergillus ochraceus micromycetes—producers of extracellular proteinases—protein C activators of blood plasma. Appl Biochem Microbiol 48, 488–492 (2012). https://doi.org/10.1134/S0003683812050109

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  • DOI: https://doi.org/10.1134/S0003683812050109

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