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In situ synthesis of calcium phosphates on chitosan macromolecules in the presence of glutamic and aspartic acids

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Abstract

Calcium hydrogen phosphate dihydrate and amorphous calcium phosphate have been synthesized in an aqueous suspension of medium molecular weight chitosan in the presence of glutamic or aspartic acid. X-ray diffraction and transmission and scanning electron microscopy characterization showed that the morphology of the phases present depended on the nature of the amino acid. The amino acids participate in the protonation of the amino groups of the chitosan and, probably, in the formation of chelate intermediate compounds with calcium ions, which act as calcium phosphate nucleation centers.

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Authors and Affiliations

  1. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninskii pr. 49, Moscow, 119991, Russia

    S. M. Barinov, A. A. Egorov, V. S. Komlev, I. V. Fadeeva & A. Yu. Fedotov

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  1. S. M. Barinov
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  2. A. A. Egorov
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  3. V. S. Komlev
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  4. I. V. Fadeeva
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  5. A. Yu. Fedotov
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Correspondence to S. M. Barinov.

Additional information

Original Russian Text © S.M. Barinov, A.A. Egorov, V.S. Komlev, I.V. Fadeeva, A.Yu. Fedotov, 2014, published in Neorganicheskie Materialy, 2014, Vol. 50, No. 7, pp. 757–760.

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Barinov, S.M., Egorov, A.A., Komlev, V.S. et al. In situ synthesis of calcium phosphates on chitosan macromolecules in the presence of glutamic and aspartic acids. Inorg Mater 50, 703–706 (2014). https://doi.org/10.1134/S0020168514070036

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  • DOI: https://doi.org/10.1134/S0020168514070036

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