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Intermolecular interactions governing solubilization in micelles of poly(alkylene oxide) surfactants

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Abstract

Partition coefficients for 39 low-molecular-mass compounds between water and micelles of an ethylene oxide-propylene oxide block copolymer (Pluronic P85) and the monolauryl ether of poly(ethylene oxide) (Brij 35) have been measured by the methods of fluorescence spectroscopy, fluorescence anisotropy, and dialysis kinetics. The tested compounds include aromatic hydrocarbons, phenols, naphthols, xanthene dyes, anthracycline antibiotics, and porphyrins. The multifactor analysis of the partition coefficients in terms of the linear free-energy relationships has been performed. It has been shown that the H-donating ability of compounds facilitates their solubilization in Pluronic micelles and has no effect on solubilization in micelles of monolauryl ether of poly(ethylene oxide). This difference indicates that, when solubilization occurs in Pluronic micelles, the compounds under study appear in a hydrophobic core composed of poly(propylene oxide) blocks.

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Authors and Affiliations

  1. Faculty of Chemistry, Moscow State University, Leninskie gory, Moscow, 119992, Russia

    V. S. Bugrin, M. Yu. Kozlov, I. I. Baskin & N. S. Melik-Nubarov

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  1. V. S. Bugrin
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  2. M. Yu. Kozlov
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  3. I. I. Baskin
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  4. N. S. Melik-Nubarov
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Additional information

Original Russian Text © V.S. Bugrin, M.Yu. Kozlov, I.I. Baskin, N.S. Melik-Nubarov, 2007, published in Vysokomolekulyarnye Soedineniya, Ser. A, 2007, Vol. 49, No. 4, pp. 701–712.

This work was supported by the Russian Foundation for Basic Research (project no. 06-03-32403) and the Federal Program for support of Leading Scientific Schools of the Russian Federation (NSh-5899.2006.3).

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Bugrin, V.S., Kozlov, M.Y., Baskin, I.I. et al. Intermolecular interactions governing solubilization in micelles of poly(alkylene oxide) surfactants. Polym. Sci. Ser. A 49, 463–472 (2007). https://doi.org/10.1134/S0965545X07040141

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  • DOI: https://doi.org/10.1134/S0965545X07040141

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