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A potentiometric sensor for the determination of diclofenac

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Abstract

A diclofenacselective electrode with a plasticized poly(vinyl chloride) membrane containing an ion associate of diclofenac with Astrafloxin FF as an electrode-active substance was developed. The linearity range of the electrode function varied from 5 × 10−5 to 5 × 10−2 M; the slope of the electrode function was 59.0 ± 1.2 mV/pc, and the working pH range was 9–12. The effectiveness of the use of this electrode for monitoring diclofenac in pharmaceutical preparations was demonstrated.

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Original Russian Text © Zh.A. Kormosh, I.P. Hunka, Ya.R. Bazel, 2009, published in Zhurnal Analiticheskoi Khimii, 2009, Vol. 64, No. 8, pp. 875–880.

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Kormosh, Z.A., Hunka, I.P. & Bazel, Y.R. A potentiometric sensor for the determination of diclofenac. J Anal Chem 64, 853–858 (2009). https://doi.org/10.1134/S1061934809080140

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  • DOI: https://doi.org/10.1134/S1061934809080140

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