Abstract
A nanomaterial comprising Fe3O4-modified hydroxylated multi-walled carbon nanotubes (Fe3O4–MWCNTs–OH) was prepared by a co-precipitation method. Combined with HPLC-photodiode array detector (DAD), Fe3O4–MWCNTs–OH was used to determine brucine in human urine. Some important parameters that could influence extraction efficiency of brucine were optimized, including the extraction time, amounts of Fe3O4–MWCNTs–OH, pH of sample solutions, desorption solvent and desorption time. Under the optimal conditions, the recoveries of brucine from spiked urine samples were between 93.1 and 104.1%, and the relative standard deviations (RSDs) ranged from 3.1 to 5.7%. The correlation coefficient was 0.9997. The limits of detection and quantification were 6 and 21 ng/mL at a signal-to-noise ratio of 3 and 10, respectively. The results indicated that Fe3O4–MWCNTs–OH combined with HPLC–DAD is a promising solid-phase extraction material for the sample pretreatment in the determination of brucine.
Similar content being viewed by others
References
Wu, W., Qiao, C., Liang, Z., Xu, H., Zhao, Z., and Cai, Z., J. Pharm. Biomed. Anal., 2007, vol. 45, p.430.
Grieve, M., A Modern Herbal: The Medical, Culinary, Cosmetic and Economic Properties, Cultivation and Folk-Lore of Herbs, Grasses, Fungi, Shrubs and Trees with their Modern Scientific Uses, London: Tiger Books, 1992, 3rd ed.
Gu, L., Wang, X., Liu, Z., Ju, P., Zhang, L., Zhang, Y., Ma, B., Bi, K., and Chen, X., Food Chem. Toxicol., 2014, vol. 68, p.226.
Rathi, A., Srivastava, N., Khatoon, S., and Rawat, A.K.S., Chromatographia, 2008, vol. 67, p.607.
Dhalwal, K. and Kadam, S.S., J. Chromatogr. Sci., 2007, vol. 45, p.706.
Bisset, N. and Fouche, P., J. Chromatogr. A, 1968, vol. 37, p.172.
Biala, R., Tits, M., Wauters, J., and Angenot, L., Fitoterapia, 1996, vol. 67, p.163.
Liu, X.Y., Zheng, S.Q., and Jiang, Z., J. Sep. Sci., 2014, vol. 37, p.764.
Frederich, M., Choi, Y., and Verporte, R., Planta Med., 2003, vol. 69, p. 1169.
Wang, C., Han, D., Wang, Z., Zang, X., and Wu, Q., Anal. Chim. Acta, 2006, vol. 572, p.190.
Zhang, Q., Xu, J., Lian, H., Li, X., and Chen, H., Anal. Bioanal. Chem., 2006, vol. 384, p.265.
Zheng, X., Xiao, H., Hoshi, T., Anzai, J., and Li, G., Microchim. Acta, 2005, vol. 152, p.69.
Valcarcel, M., Cardenas, S., and Simonet, B.M., Anal. Chem., 2007, vol. 79, p. 4788.
Zhu, Y., Murali, S., Cai, W., Li, X., Suk, J., and Potts, J.R., Adv. Mater., 2010, vol. 22, p. 3906.
Liu, Q., Shi. J., Zeng, L., Wang, T., Cai, Y., and Jiang, G., J. Chromatogr. A, 2011, vol. 1218, p.197.
Chen, H., Deng, C., and Zhang, X., Angew. Chem., Int. Ed., 2010, vol. 49, p.607.
Song, X.Y., Shi, Y.P., and Chen, J., Talanta, 2013, vol. 116, p.188.
Pietsch, J., Gunther, J., Henle, T., and Dressler, J., J. Sep. Sci., 2008, vol. 31, p. 2410.
Liu, Y., Zhu, R., Li, H., Yan, M., and Lei, Y., J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2011, vol. 879, p. 2714.
Chen, X., Lai, Y., and Cai, Z., J. Anal. Toxicol., 2012, vol. 36, p. 171.
Author information
Authors and Affiliations
Corresponding author
Additional information
The article is published in the original.
Rights and permissions
About this article
Cite this article
Feng, Z., Yang, R. & Du, B. Fast SPE and HPLC–DAD determination of brucine in human urine using multi-walled carbon nanotubes modified with magnetic nanoparticles. J Anal Chem 72, 862–869 (2017). https://doi.org/10.1134/S1061934817080159
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1061934817080159