Skip to main content
SpringerLink
Log in

Prospects for the Use of Bismuth Nanoparticles and Its Compounds in Biomedicine

  • MEDICAL PHYSICS AND BIOPHYSICS
  • Published:
Physics of Atomic Nuclei Aims and scope Submit manuscript

Abstract

The article analyzes the modern directions of biomedical applications of bismuth nanoparticles. The works demonstrating the use of bismuth nanoparticles as a contrast agent for visualization, as an agent for phototherapy, and as a basis for antibacterial drugs are considered. Emphasis is placed on the theranostic applications of this new material, which are extremely important for the problems of early diagnosis and minimally invasive localized treatment of cancer. Bismuth is considered as a radionuclide for nuclear medicine. Such important questions as biocompatibility, toxicity, and excretion from the body are raised.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.

REFERENCES

  1. Yu. M. Yukhin, E. S. Koledova, and O. A. Logutenko, Bismuth and its Compounds in Medicine (Russ. Akad. Nauk, Moscow, 2022), p. 234 [in Russian].

    Google Scholar 

  2. S. V. Okovity and D. Yu. Ivkin, Lechashch. Vrach., No. 10, 67 (2015).

  3. A. S. Gorshkova, V. D. Rumyantseva, and A. F. Mironov, Tonk. Khim. Tekhnol. 13 (2), 5 (2018).

    CAS  Google Scholar 

  4. T. A. Ilchishina, Ross. Zh Gastroenterol., Gepatol., Koloproktol., No. 31, 51 (2021).

  5. O. N. Minushkin, T. B. Topchiy, and A. M. Chebotareva, Med. Sovet, No. 15, 18 (2017).

  6. E. Yu. Plotnikova and A. S. Sukhikh, Lechashch. Vrach., No. 2, 60 (2016).

  7. O. A. Jerry and C. O. Damian, Molecules 25, 305 (2020).

    Article  Google Scholar 

  8. M. K. Donal and M. G. Darren, Molecules 19, 15258 (2014).

    Article  Google Scholar 

  9. Yifan Hong, Angel Yau-Tsz Lai, G. C. F. Chan, and H. Sun, Proc. Natl. Acad. Sci. U. S. A. 112, 3211 (2015).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  10. K. Petsoma, A. Kopwitthayab, M. Horphathumc, J. Kaewkhaoa, N. Sangwaranateee, and H. Kim, Mater Today. 5, 14960 (2018).

    Google Scholar 

  11. L. N. Borovikova, I. V. Polyakova, E. M. Korotkikh, V. K. Lavrentiev, A. I. Kipper, and O. A. Pisarev, J. Phys. Chem. 92, 1760 (2018).

    Google Scholar 

  12. D. Ma, J. Zhao, Y. Zhao, X. L. Hao, and Y. Lu, Chem. Eng. J. 209, 273 (2012).

    Article  CAS  Google Scholar 

  13. G. V. Tikhonowski, A. A. Popov, A. A. Kurinnaya, A. A. Garmash, E. V. Gromushkina, I. N. Zavestovskaya, S. M. Klimentov, and A. V. Kabashin, Bull. Lebedev Phys. Inst., No. 49, 180 (2022).

  14. Ji-jun Fu, Jun-jie Guo, Ai-ping Qin, Xi-yong Yu, Qiang Zhang, Xue-ping Lei, Yu-gang Huang, Ming-yue Chen, et al., J. Nanobiotechnol. 18, 110 (2020).

    Article  CAS  Google Scholar 

  15. V. I. Baryshov, Med. Alfavit 3 (33), 37 (2017).

    Google Scholar 

  16. C. Liu, L. Zhang, X. Chen, S. Li, Q. Han, L. Li, and C. Wang, Chem. Eng. J. 382, 122720 (2020).

  17. H. Zhao, J. Wang, X. Li, Y. Li, C. Li, X. Wang, J. Wang, S. Guan, Y. Xu, G. Deng, et al., J. Colloid Interface Sci. 604, 80 (2021).

    Article  ADS  CAS  PubMed  Google Scholar 

  18. Y.  Xuan,  X.-Q.  Yang,  Z.-Y.  Song,  R.-Y.  Zhang, D.-H. Zhao, X.-L. Hou, X.-L. Song, B. Liu, Y.-D. Zhao, and W. Chen, Adv. Funct. Mater. 29, 1900017 (2019).

  19. H. Yu, H. Guo, Y. Wang, Y. Wang, and L. Zhang, WIREs Nanomed. Nanobiotechnol. 14, e1801 (2022).

  20. M.-A. Shahbazi, L. Faghfouri, M. P. A. Ferreira, P. Figueiredo, H. Maleki, F. Sefat, de Jouni Hirvonen, and H. A. Santos, Chem. Soc. Rev., No. 4, 1253 (2020).

  21. C. Stewart, K. Konstantinov, S. McKinnon, S. Guatelli, M. Lerch, A. Rosenfeld, M. Tehei, and S. Corde, Phys. Med. 32, 1444 (2016).

    Article  PubMed  Google Scholar 

  22. A. Azad, S. Rostamifar, F. Modaresi, A. Bazrafkan, and Z. Rezaie, BioMed Res. Int. 2020, 5465439 (2020).

  23. S. Rostamifar, A. Azad, A. Bazrafkan, F. Modaresi, S. Atashpour, and Z. K. Jahromi, BioMed Res. Int. 2021, 6695692 (2021).

  24. S. K. Zyryanov and K. E. Zatolochina, Kachestv. Klin. Prakt., No. 2, 51 (2018).

  25. P. P. Boldyrev, N. Yu. Kochetkova, M. A. Proshin, R. F. Nurtdinov, and A. N. Semenov, Med. Phys., No. 1, 64 (2015).

  26. S. Ahenkorah, Ch. M. Deroose, Th. Cardinaels, and I. Cassells, Pharmaceutics 13, 599 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. S. Franchi, M. Tosato, and V. B. di Marco, Nucl. Med. Biol. 114–115, 168 (2022).

    Article  PubMed  Google Scholar 

  28. S. Badrigilan, F. Heydarpanahi, J. Choupani, M. Jaymand, H. Samadian, M. Hoseini-Ghahfarokhi, Th. J. Webster, and L. Tayebi, Int. J. Nanomed. 15, 7079 (2020).

    Article  CAS  Google Scholar 

Download references

Funding

This work was supported by the Ministry of Science and Higher Education of the Russian Federation, project no. 075-15-2021-1347.

Author information

Authors and Affiliations

  1. National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), 115409, Moscow, Russia

    A. V. Rudyy, A. A. Fronya & I. N. Zavestovskaya

  2. Lebedev Physical Institute, Russian Academy of Sciences, 119991, Moscow, Russia

    A. V. Rudyy, A. A. Fronya & I. N. Zavestovskaya

Authors
  1. A. V. Rudyy
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. A. Fronya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I. N. Zavestovskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A. V. Rudyy.

Ethics declarations

The authors of this work declare that they have no conflicts of interest.

Additional information

Translated by O. Pismenov

Publisher’s Note.

Pleiades Publishing remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rudyy, A.V., Fronya, A.A. & Zavestovskaya, I.N. Prospects for the Use of Bismuth Nanoparticles and Its Compounds in Biomedicine. Phys. Atom. Nuclei 86, 2507–2512 (2023). https://doi.org/10.1134/S106377882311039X

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S106377882311039X

Keywords:

Search

Navigation