Abstract
Synthesis of some new oxomolybdenum(V) and dioxomolybdenum(VI) complexes with a Schiff base isonicotinioyl(5-bromo-2-hydroxybenzylidene)hydrazide (L) derived from 5-bromosalicylaldehyde and isonicotinoylhydrazide are reported. The complexes have been characterized by elemental analyses, molar conductance, magnetic susceptibility data, IR, UV-Vis, EPR, 1H NMR, and FAB mass spectral studies. The physicochemical studies and spectral data indicate that L acts as a monovalent tridentate chelating agent. The FAB mass and X-band EPR spectra indicate that the pentavalent Mo in the complex is monomeric in nature. The X-ray diffraction studies of the complex [MoO(L)Cl2] (I) correspond to the orthorhombic crystal lattice with the unit cell dimensions a = 16.11, b = 12.20, and c = 7.5 Å. The electrochemical behavior of the complex was investigated by cyclic voltammetry. All the complexes are found to be neutral with the distorted octahedral geometry. The thermal properties of the complex I were investigated by thermogravimetric techniques. The ligand L and the complexes I and [MoO2(L)Cl] (II) were screened for their in vitro antimicrobial activity. The complexes exhibited higher activity than L. The 3D molecular modeling and analysis for bond length and bond angles have also been carried out for complex I.
Similar content being viewed by others
References
Steifel, E.I., Prog. Inorg. Chem., 1977, vol. 22, p. 1.
Prabhakaran, C.P. and Nair, B.G., Transition Met. Chem., 1983, vol. 8, no. 3, p. 68.
Harikumaran Nair, M.L. and Sheela, A., Indian J. Chem., Sect. A: Inorg., Bio-inorg., Phys., Theor. Anal. Chem., 2008, vol. 47, p. 1787.
Harikumaran Nair, M.L. and Kumari Nisha, K.R., Asian J. Chem., 2007, vol. 19, no. 6, p. 4487.
Harikumaran Nair, M.L. and Siji, V.L., J. Indian Chem. Soc., 2009, vol. 86, p. 441.
Gnecco, J.A., Borda, G., and Reyes, P., J. Chil. Chem. Soc., 2004, vol. 49, no. 2, p. 179.
Tamm, M., Dresel, B., Urban, V., et al., Inorg. Chem. Commun., 2002, vol. 5, no. 10, p. 837.
Bandyopadhyay, R., Biswas, S., Guha, S., et al., J. Chem. Soc., Chem. Commun., 1999, p. 1627.
Rollas, S. and Küçükgüzel, Ş.G., Molecules, 2007, vol. 12, p. 1910.
Chohan, Z.H., Arif, M., Shafiq, Z., et al., J. Enz. Inhib. Med. Chem., 2006, vol. 21, no. 1, p. 95. S
Harikumaran Nair, M.L. Sheela, A., and Prameela Gladis, M.S., J. Indian Chem. Soc., 2007, vol. 84, p. 329.
Harikumaran Nair, M.L. and Prabhakaran, C.P., Indian J. Chem., Sect. A: Inorg., Bio-inorg., Phys., Theor. Anal. Chem., 1998, vol. 37, p. 452.
Vogel, A.I., A Text Book of Quantitative Inorganic Analysis, ELBS Longman, 1963.
Dutta, R.L. and Syamal, A., Elements of Magnetochemistry, New Delhi: East West, 1992, p. 8.
Ananthanarayan, R. and Panikar, J.C., Text Book of Microbiology, Hyderabad: Orient Longman, 1999, p. 578
Prabhakaran, C.P. and Harikumaran Nair, M.L., J. Indian Chem. Soc., 1998, vol. 75, p. 7.
Mishra, A.P. and Soni, M., Metal-Based Drugs, DOI: 10.1155/2008/875410.
Murukan, B. and Mohanan, K., J. Enz. Inhib. Med. Chem., 2006, vol. 22, no.1, p. 1
Singh, N., Hingorani, S., Srivastava, J., et al., Synth. React. Inorg. Met-Org. Chem., 1992, vol. 22, no. 9, p. 1283.
Singh, K., Agarwala, B.V., and Naganagowda, G.A., Indian J. Chem., Sect. A: Inorg., Bio-inorg., Phys., Theor. Anal. Chem., 1996, vol. 35, p. 66.
Nakamoto, K., Infrared and Raman Spectra of Inorganic and Coordination Compounds, New York: Wiley, 1978.
Harikumaran Nair, M.L. and Prabhakaran, C.P., Indian J. Chem., Sect. A: Inorg., Bio-inorg., Phys., Theor. Anal. Chem., 2000, vol. 39, p. 989.
Mandlik, P., More, M.B., and Aswar, A.S., Indian J. Chem., Sect. A: Inorg., Bio-inorg., Phys., Theor. Anal. Chem., 2003, vol. 42, p. 1064.
Harikumaran Nair, M.L. and Prabhakaran, C.P., J. Teach. Res. Chem., 1996, vol. 3, no. 2, p. 25.
Sharma, V.K., Srivastava., A., and Srivastava., S., J. Serb. Chem. Soc., 2006, vol. 71, nos. 8–9, p. 917.
Abragam, A. and Bleaney, B., Electron Paramagnetic Resonance of Transition Metal Ions, Oxford: Clarendon, 1970.
Hesse, R., Acta Crystallogr., 1948, vol. 1, p. 200.
Lipson, H., Acta Crystallogr., 1949, vol. 2, p. 43.
Singh, V.P., Katiyar, A., and Singh, S., Biometals, 2008, vol. 21, p. 491.
Mohanan, K., Nirmala Devi, S., and Murukan, B., Synth. React. Inorg. Met-Org. Chem., 2006, vol. 36, p. 441.
Koh, L., Kon, O.L., Loh, K.W., et al., J. Inorg. Biochem., 1998, vol. 72, p. 155.
Agarwal, R.K., Sharma, D., Singh, L., et al., Bioinorg. Chem. Appl., 2006, Doi: 10.1156/BCA/2006/29234.
C.S. Chem. 3D Ultra Molecular Modeling and Analysis Cambridge, http://www.cambridgesoft.com
Maurya, R.C., Pandey, A., Chaurasia, J., et al., J. Mol. Struct., 2006, vol. 798, p. 89.
Author information
Authors and Affiliations
Corresponding author
Additional information
The article is published in the original.
Rights and permissions
About this article
Cite this article
Harikumaran Nair, M.L., Thankamani, D. Synthesis, physicochemical, antimicrobial, and 3D molecular modeling studies of oxomolybdenym(V) and dioxomolybdenum(VI) complexes with a Schiff base isonicotinoyl(5-bromo-2-hydroxybenzylidene)hydrazide. Russ J Coord Chem 36, 259–268 (2010). https://doi.org/10.1134/S1070328410040044
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1070328410040044