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Steric structure of N-(2-Hydrazono-2-hydroxyethyl)-d-pseudoephedrine and its intramolecular heterocyclization under the action of orthoformic ester

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Abstract

An X-ray structural investigation of N-(2-hydrazono-2-hydroxyethyl)-d-pseudoephedrine is performed, and intramolecular heterocyclization of this compound with orthoformic ester is studied. The final reaction product is found to be a compound containing a morpholone ring rather than substituted 1,3,4-oxadiazole.

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Authors and Affiliations

  1. Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, ul. Alikhanova 1, Karaganda, 470061, Kazakhstan

    I. V. Kulakov, O. A. Nurkenov, A. A. Ainabaev & A. M. Gazaliev

  2. Institute of Phytochemistry of the Republic of Kazakhstan, Karaganda, Kazakhstan

    D. M. Turdybekov & K. M. Turdybekov

Authors
  1. I. V. Kulakov
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  2. O. A. Nurkenov
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  3. A. A. Ainabaev
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  4. D. M. Turdybekov
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  5. K. M. Turdybekov
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  6. A. M. Gazaliev
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Corresponding author

Correspondence to I. V. Kulakov.

Additional information

Original Russian Text © I.V. Kulakov, O.A. Nurkenov, A.A. Ainabaev, D.M. Turdybekov, K.M. Turdybekov, A.M. Gazaliev, 2007, published in Zhurnal Obshchei Khimii, 2007, Vol. 77, No. 9, pp. 1538–1541.

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Kulakov, I.V., Nurkenov, O.A., Ainabaev, A.A. et al. Steric structure of N-(2-Hydrazono-2-hydroxyethyl)-d-pseudoephedrine and its intramolecular heterocyclization under the action of orthoformic ester. Russ J Gen Chem 77, 1610–1613 (2007). https://doi.org/10.1134/S1070363207090186

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  • DOI: https://doi.org/10.1134/S1070363207090186

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