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Synthesis, structure and chemical transformations of 4-aminobenzaldehyde

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Abstract

A possibility of nucleophilic substitution of the fluorine atom in 4-fluorobenzaldehyde with amines (morpholine, piperidine or cytisine) under convection heating and microwave irradiation was shown. Reactions of 4-morpholinyl- and 4-piperidinylbenzaldehyde with hydrazides of isonicotinic and salicylic acids afford the corresponding hydrazones. The structure of the synthesized compounds was confirmed by IR, 1H NMR spectroscopy, mass spectrometry, and X-ray analysis data.

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Authors and Affiliations

  1. Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, ul. Alikhanova 1, Karaganda, 100008, Kazakhstan

    O. A. Nurkenov, S. D. Fazylov & A. E. Arinova

  2. International Research and Production Holding “Phytochemistry,”, Karaganda, Kazakhstan

    K. M. Turdybekov

  3. Multiple-Discipline Humanitarian-Technical University, Karaganda, Kazakhstan

    D. M. Turdybekov

  4. Academician Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan

    S. A. Talipov & B. T. Ibragimov

Authors
  1. O. A. Nurkenov
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  2. S. D. Fazylov
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  3. A. E. Arinova
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  4. K. M. Turdybekov
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  5. D. M. Turdybekov
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  6. S. A. Talipov
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  7. B. T. Ibragimov
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Corresponding author

Correspondence to O. A. Nurkenov.

Additional information

Original Russian Text © O.A. Nurkenov, S.D. Fazylov, A.E. Arinova, K.M. Turdybekov, D.M. Turdybekov, S.A. Talipov, B.T. Ibragimov, 2013, published in Zhurnal Obshchei Khimii, 2013, Vol. 83, No. 10, pp. 1654–1659.

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Nurkenov, O.A., Fazylov, S.D., Arinova, A.E. et al. Synthesis, structure and chemical transformations of 4-aminobenzaldehyde. Russ J Gen Chem 83, 1864–1868 (2013). https://doi.org/10.1134/S1070363213100113

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  • DOI: https://doi.org/10.1134/S1070363213100113

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