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N-hetaryl-2-cyanoacetamides in the synthesis of substituted (E)-N-hetaryl-2-cyanoacrylamides, (E)-N-alkyl-N-hetaryl-2-cyanoacrylamides, and 6-amino-2-oxo-4-phenyl-1-(pyridin-2-yl)-1,2-dihydropyridine-3,5-dicarbonitriles

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Abstract

Knoevenagel condensation of N-hetaryl-substituted cyanoacetamides with aldehydes gave the corresponding (E)-N-hetaryl-2-cyanoacrylamides which were converted into (E)-N-alkyl-N-hetaryl-2-cyanoacrylamides and 6-amino-2-oxo-4-phenyl-1-(pyridin-2-yl)-1,2-dihydropyridine-3,5-dicarbonitriles. The structure of (E)-N-(pyridin-2-yl)-2-cyano-3-phenylprop-2-enamide was determined by X-ray analysis.

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Authors and Affiliations

  1. Taras Shevchenko National Pedagogical University, ul. Oboronnaya 2, Lugansk, 91011, Ukraine

    I. V. Dyachenko & V. D. Dyachenko

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, ul. Murmanskaya 5, Kiev, 02660, Ukraine

    E. B. Rusanov

Authors
  1. I. V. Dyachenko
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  2. V. D. Dyachenko
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  3. E. B. Rusanov
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Original Russian Text © I.V. Dyachenko, V.D. Dyachenko, E.B. Rusanov, 2007, published in Zhurnal Organicheskoi Khimii, 2007, Vol. 43, No. 1, pp. 81–86.

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Dyachenko, I.V., Dyachenko, V.D. & Rusanov, E.B. N-hetaryl-2-cyanoacetamides in the synthesis of substituted (E)-N-hetaryl-2-cyanoacrylamides, (E)-N-alkyl-N-hetaryl-2-cyanoacrylamides, and 6-amino-2-oxo-4-phenyl-1-(pyridin-2-yl)-1,2-dihydropyridine-3,5-dicarbonitriles. Russ J Org Chem 43, 83–89 (2007). https://doi.org/10.1134/S1070428007010101

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  • DOI: https://doi.org/10.1134/S1070428007010101

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