Skip to main content
Log in

Transamination of α-amino nitriles

  • Published:
Russian Journal of Organic Chemistry Aims and scope Submit manuscript

Abstract

α-Amino nitriles containing a primary amino group undergo transamination with aliphatic and aromatic amines under mild conditions with high yields. A probable reaction mechanism involving intermediate elimination of cyanide ion has been proposed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Strecker, A., Ann. Chem. Pharm., 1850, vol. 75, p. 27.

    Article  Google Scholar 

  2. Bucherer, H.T. and Steiner, W., J. Prakt. Chem., 1934, vol. 140, p. 291.

    CAS  Google Scholar 

  3. Evans, D.A., Truesdale, L.K., and Carroll, G.L., J. Chem. Soc., Chem. Commun., 1973, p. 55.

    Google Scholar 

  4. Bauer, O.W. and Teter, J.W., US Patent no. 2 552 026; Chem. Abstr., 1951, vol. 45, p. 9074.

    Google Scholar 

  5. Domkin, V.D. and Kur’yanovich, A.A., Zh. Org. Khim., 1976, vol. 12, p. 908.

    CAS  Google Scholar 

  6. Brown, T., Shaw, G., and Durant, G.J., J. Chem. Soc., Perkin Trans. 1, 1980, p. 2310.

    Google Scholar 

  7. Popov, Yu.V., Mokhov, V.M., Tankabekyan, N.A., and Safronova, O.Yu., Russ. J. Appl. Chem., 2012, vol. 85, p. 1387.

    Article  CAS  Google Scholar 

  8. Shakhidayatov, Kh., Zh. Org. Khim., 1973, vol. 9, p. 1373.

    Google Scholar 

  9. Shafran, Yu.M., Bakulev, V.A., and Mokrushin, V.S., Usp. Khim., 1989, vol. 58, p. 250.

    Article  CAS  Google Scholar 

  10. Freifelder, M. and Hasbrouck, R.B., J. Am. Chem. Soc., 1960, vol. 82, p. 696.

    Article  CAS  Google Scholar 

  11. Popov, Yu.V., Mokhov, V.M., and Tankabekyan, N.A., Russ. J. Org. Chem., 2013, vol. 49, p. 1135.

    Article  CAS  Google Scholar 

  12. Wendelin, W., Kern, W., Zmolnig, I., and Schramm, H., Monatsh. Chem., 1981, vol. 112, p. 1091.

    Article  CAS  Google Scholar 

  13. Barreau, M., Chottard, J.-C., Le Peco, J-B., and Mailliet, P., US Patent no. 5 225 207, 1993.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Yu. V. Popov.

Additional information

Original Russian Text © Yu.V. Popov, V.M. Mokhov, N.A. Tankabekyan, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 1, pp. 29–32.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Popov, Y.V., Mokhov, V.M. & Tankabekyan, N.A. Transamination of α-amino nitriles. Russ J Org Chem 50, 21–24 (2014). https://doi.org/10.1134/S1070428014010047

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070428014010047

Keywords

Navigation