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Synthesis of cyclohexyl isovalerate by carbonylation of isobutylene with carbon monoxide and cyclohexanol in the presence of Pd(PPh3)4‒PPh3‒TsOH and its antimicrobial activity

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Abstract

A procedure has been developed for the synthesis of cyclohexyl isovalerate by reaction of isobutylene with carbon monoxide and cyclohexanol in the presence of the three-component catalytic system Pd(PPh3)4‒PPh3‒TsOH. Cyclohexyl isovalerate showed a pronounced antibacterial activity.

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Authors and Affiliations

  1. Korkyt Ata Kyzylorda State University, ul. Aiteke bi 29A, Kyzylorda, 120014, Kazakhstan

    N. O. Appazov, S. S. Seitzhanov, A. T. Zhunissov & R. A. Narmanova

Authors
  1. N. O. Appazov
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  2. S. S. Seitzhanov
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  3. A. T. Zhunissov
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  4. R. A. Narmanova
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Correspondence to N. O. Appazov.

Additional information

Original Russian Text © N.O. Appazov, S.S. Seitzhanov, A.T. Zhunissov, R.A. Narmanova, 2017, published in Zhurnal Organicheskoi Khimii, 2017, Vol. 53, No. 10, pp. 1560–1561.

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Appazov, N.O., Seitzhanov, S.S., Zhunissov, A.T. et al. Synthesis of cyclohexyl isovalerate by carbonylation of isobutylene with carbon monoxide and cyclohexanol in the presence of Pd(PPh3)4‒PPh3‒TsOH and its antimicrobial activity. Russ J Org Chem 53, 1596–1597 (2017). https://doi.org/10.1134/S1070428017100189

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  • DOI: https://doi.org/10.1134/S1070428017100189

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