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Interaction of titanium dioxide nanoparticles with influenza virus

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Abstract

Titanium dioxide (TiO2) in a suspension or absorbed on a film possesses bactericidal and virucidal properties caused by photocatalytic reactions. Our electron microscopic examinations showed that titanium dioxide nanoparticles destroyed the influenza virus after 30 min incubation. Virological studies revealed the inactivation of the influenza virus by TiO2, depending on the concentration of nanoparticles and the incubation period. The inactivation effect was observed when the incubation was performed in darkness, unlike the TiO2 suspension. We propose that the virus-inactivation properties of TiO2 are mainly based on the direct contact between nanoparticles and virus particles.

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Authors and Affiliations

  1. Novosibirsk State University, ul. Pirogova 2, Novosibirsk, 630090, Russia

    N. A. Mazurkova, Yu. E. Spitsyna, S. N. Zagrebel’nyi & E. I. Ryabchikova

  2. Vector State Scientific Center for Virology and Biotechnology, r.p. Kol’tsovo, Novosibirsk oblast, 630559, Russia

    N. A. Mazurkova

  3. Boreskov Institute of Catalysis, Siberian Branch, Russian Academy of Sciences, pr. Akademika Lavrent’eva 5, Novosibirsk, 630090, Russia

    N. V. Shikina & Z. R. Ismagilov

  4. Institute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, pr. Akademika Lavrent’eva 8, Novosibirsk, 630090, Russia

    Yu. E. Spitsyna & E. I. Ryabchikova

Authors
  1. N. A. Mazurkova
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  2. Yu. E. Spitsyna
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  3. N. V. Shikina
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  4. Z. R. Ismagilov
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  5. S. N. Zagrebel’nyi
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  6. E. I. Ryabchikova
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Corresponding author

Correspondence to S. N. Zagrebel’nyi.

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Original Russian Text © N.A. Mazurkova, Yu.E. Spitsyna, N.V. Shikina, Z.R. Ismagilov, S.N. Zagrebel’nyi, E.I. Ryabchikova, 2010, published in Rossiiskie nanotekhnologii, 2010, Vol. 5, Nos. 5–6.

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Mazurkova, N.A., Spitsyna, Y.E., Shikina, N.V. et al. Interaction of titanium dioxide nanoparticles with influenza virus. Nanotechnol Russia 5, 417–420 (2010). https://doi.org/10.1134/S1995078010050174

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  • DOI: https://doi.org/10.1134/S1995078010050174

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