Abstract
Data on the antimicrobial effect of copper nanoparticles with different sizes, phase compositions, and surface oxide film thicknesses are represented. The nanoparticles under study show an antibacterial effect against the cells of the test species, Gram positive (Staphylococcus albus) and Gram negative (Escherihia coli) strains. The differences in toxicity observed for nanoparticles with varying dispersions and phase compositions are related to both specific features of the microorganism strains and nanoparticle concentration and properties.
Similar content being viewed by others
References
J. B. Wright, K. Lam, A. G. Buret, et al., “Early healing events in a porcine model of contaminated wounds: effects of nanocrystalline silver on matrix metalloproteinases, cell apoptosis, and healing,” Wound Repair Regen. 10(3), 141–151 (2002).
A. A. Rakhmetova, T. P. Alekseeva, O. A. Bogoslovskaya, et al., “Wound-healing properties of copper nanoparticles as a function of physicochemical parameters,” Nanotech. Russ. 5(3–4), 271 (2010).
O. A. Bogoslovskaya, A. A. Rakhmetova, N. N. Glushchenko, M. N. Ovsyannikova, I. P. Ol’khovskaya, V. P. Varlamov, A. N. Levov, A. V. Il’ina, and A. A. Zubareva, RF Patent No. 2460532, 2012.
N. N. Glushchenko, O. A. Bogoslovskaya, and I. P. Ol’khovskaya, “Physicochemical regularities of biological activity of high-dispersed metal powders,” Khim. Fiz. 21(4), 79–85 (2002).
O. A. Bogoslovskaya, A. A. Rakhmetova, I. P. Ol’khovskaya, I. O. Leipunskii, and N. N. Glushchenko, “The way to estimate component safety of heavy particles from smokes caused by acombined heat and power plants: copper nanoparticles with modified surface,” Izv. Akad. Nauk. Energet., No. 3, 97–104 (2012).
S. Pal, K. Yu, and J. M. Song, “Does the antibacterial activity of silver nanoparticles depend on the shape of nanoparticle? A study of the gram-negative bacterium E. coli,” Appl. Envir. Microbiol. 73(6), 1712–1720 (2007).
P. L. Taylor, O. Omotoso, J. B. Wiskel, et al., “Impact of heat on nanocrystalline silver dressings. Part II: physical properties,” Biomaterials 26(35), 7230–7240 (2005).
M. Ya. Gen and A. V. Miller, USSR Inventor’s Certificate No. 814432, Byull. Izobret., No. 11 (1981).
A. N. Zhigach, I. O. Leipunskii, M. L. Kuskov, et al., “Facility for producing metallic nanoparticles and for investigating their physicochemical properties,” Prib. Tekh. Eksp., No. 6, 122–129 (2000).
The Way to Determine Microorganisms Sensibility to Antimicrobials. Methodological Recommendations (Federal. tsentr Gossanepidnadzora Minzdrava Rossii, 2004).
J. Ramyadevi, K. Jeyasubramanian, A. Marikani, G. Rajakumar, and A. A. Rahuman, “Synthesis and antimicrobial activity of copper nanoparticles,” Mater. Lett. 71, 114–116 (2012).
K. Y. Yoon, J. H. Byeon, J. H. Park, and J. Hwang, “Susceptibility constants of Escherichia coli and bacillus subtilis to silver and copper nanoparticles,” Sci. Total Environ. 373, 572–575 (2007).
A. Azam, A. S. Ahmed, M. Oves, M. S. Khan, and A. Memic, “Size-dependent antimicrobial properties of CuO nanoparticles against gram-positive and -negative bacterial strains,” Int. J. Nanomed. 7, 3527–3535 (2012).
H. Sakhawat, K. F. Ummul, A. M. Yousuf, R. Muhibur, et al., “Microemulsions as nanoreactor for preparation of nanoparticles with antibacterial activity,” J. Bangladesh Chem. Soc. 25(1), 71–79 (2012).
J. P. Ruparelia, A. K. Chatterjee, S. P. Duttagupta, and S. Mukherji, “Strain specificity in antimicrobial activity of silver and copper nanoparticles,” Acta Biomater. 4, 707–716 (2008).
S. Jadhav, S. Gaikwad, M. Nimse, and A. Rajbhoj, “Copper oxide nanoparticles: synthesis, characterization and their antibacterial activity,” J Clust. Sci. 22, 121–129 (2011).
Author information
Authors and Affiliations
Additional information
Original Russian Text © O.A. Bogoslovskaja, A.A. Rakhmetova, M.N. Ovsyannikova, I.P. Olkhovskaya, N.N. Gluschenko, 2014, published in Rossiiskie Nanotekhnologii, 2014, Vol. 9, Nos. 1–2.
Rights and permissions
About this article
Cite this article
Bogoslovskaja, O.A., Rakhmetova, A.A., Ovsyannikova, M.N. et al. Antimicrobial effect of copper nanoparticles with differing dispersion and phase composition. Nanotechnol Russia 9, 82–86 (2014). https://doi.org/10.1134/S1995078014010042
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1995078014010042