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Metabolomics: On the way to an integration of biochemistry, analytical chemistry, and informatics

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Abstract

The review considers the development of a new science—metabolomics. The metabolome is mainly regarded as a set of primarily biochemical parameters, each of which or their ratio can serve as a potential biomarker that increases the sensitivity and/or specificity of diagnostics of diseases.

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  1. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Toreza 44, St. Petersburg, 194223, Russia

    N. V. Goncharov & N. G. Voitenko

  2. Research Institute of Hygiene, Occupational Pathology, and Human Ecology, St. Petersburg, 192019, Russia

    N. V. Goncharov, A. I. Ukolov, T. I. Orlova, E. D. Migalovskaia & N. G. Voitenko

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  1. N. V. Goncharov
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Original Russian Text © N.V. Goncharov, A.I. Ukolov, T.I. Orlova, E.D. Migalovskaia, N.G. Voitenko, 2015, published in Uspekhi Sovremennoi Biologii, 2015, Vol. 135, No. 1, pp. 3–17.

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Goncharov, N.V., Ukolov, A.I., Orlova, T.I. et al. Metabolomics: On the way to an integration of biochemistry, analytical chemistry, and informatics. Biol Bull Rev 5, 296–307 (2015). https://doi.org/10.1134/S2079086415040027

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