Papers And Originals
Double-blind Trial of Linoleate Supplementation of the Diet in Multiple Sclerosis
Br Med J 1973; 1 doi: https://doi.org/10.1136/bmj.1.5856.765 (Published 31 March 1973) Cite this as: Br Med J 1973;1:765
- J. H. D. Millar,
- K. J. Zilkha,
- M. J. S. Langman,
- H. Payling Wright,
- A. D. Smith,
- J. Belin,
- R. H. S. Thompson
Abstract
Seventy-five patients in London and Belfast with multiple sclerosis were given daily supplements of a vegetable oil mixture containing either linoleate or oleate for two years in a double-blind control trial. Relapses tended to be less frequent and were significantly less severe and of shorter duration in the linoleate-supplemented group than in those receiving the oleate mixture, but clear evidence that treatment affected the overall rate of clinical deterioration was not obtained.