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We thank Mathian et al for reporting the outcomes of COVID-19 disease in a series of 17 patients with systemic lupus erythematosus (SLE) from several hospitals across France.1 In a context where there is substantial interest in the role of hydroxychloroquine (HCQ) as a potential preventive or therapeutic agent for severe acute respiratory syndrome–coronavirus-2 (SARS-CoV-2), these cases are noteworthy.
While the authors have correctly acknowledged the limitations of this case series report, we wish to emphasise several important points that impact the interpretation of the findings. The denominator of all patients with lupus on hydroxychloroquine who are ‘at risk’ of COVID-19 in this setting is unknown and may indeed be impossible to even estimate as it would need to …
Footnotes
Contributors MN authored this correspondence with contribution from BT, IPW and MP.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; internally peer reviewed.