Letters
Authors' reply
BMJ 1995; 310 doi: https://doi.org/10.1136/bmj.310.6980.667a (Published 11 March 1995) Cite this as: BMJ 1995;310:667- Lyn March,
- Jennifer Schwarz,
- Les Irwig,
- Judy Simpson,
- Catherine Chock,
- Peter Brooks
- Research fellow Research assistant Florance and Cope Professorial Department of Rheumatology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia
- Associate professor NSAHS Public Health Unit and Department of Public Health, University of Sydney, NSW 2006
- Senior lecturer in biostatics Research assistant Department of Public Health, University of Sydney, NSW 2006
- Professor of medicine St Vincent's Hospital, Darlinghurst, NSW 2010
EDITOR,—We regard n of 1 trials as a useful tool to help a patient and practitioner decide whether non-steroidal anti-inflammatory drugs offer appreciably better relief than paracetamol. Only then do we think it worth using non-steroidal anti-inflammatory drugs, given their risk of serious side effects. The conceptual bias discussed by C J Hawkey is not a bias but rather our view of sensible decision making. Nor is statistical bias an issue because the decision about treatment was made not …
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