References

1. J. Panés, “Inflammatory bowel disease: pathogenesis and targets for therapeutic interventions,” Acta Physiologica Scandinavica, vol. 173, no. 1, pp. 159–165, 2001.

   View at: Publisher Site | Google Scholar

2. Y. H. Kho, M. Oudkerk Pool, F. G. A. Jansman, and J. W. Harting, “Pharmacotherapeutic options in inflammatory bowel disease: an update,” Pharmacy World & Science, vol. 23, no. 1, pp. 17–21, 2001.

   View at: Publisher Site | Google Scholar

3. T. Hong, G.-B. Jin, G. Yoshino et al., “Protective effects of Polygalae root in experimental TNBS-induced colitis in mice,” Journal of Ethnopharmacology, vol. 79, no. 3, pp. 341–346, 2002.

   View at: Publisher Site | Google Scholar

4. K. Sugimoto, H. Hanai, K. Tozawa et al., “Curcumin prevents and ameliorates trinitrobenzene sulfonic acid-induced colitis in mice,” Gastroenterology, vol. 123, no. 6, pp. 1912–1922, 2002.

   View at: Publisher Site | Google Scholar

5. S. Maity, A. Ukil, S. Karmakar et al., “Thearubigin, the major polyphenol of black tea, ameliorates mucosal injury in trinitrobenzene sulfonic acid-induced colitis,” European Journal of Pharmacology, vol. 470, no. 1-2, pp. 103–112, 2003.

   View at: Publisher Site | Google Scholar

6. A. Ukil, S. Maity, S. Karmakar, N. Datta, J. R. Vedasiromoni, and P. K. Das, “Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis,” British Journal of Pharmacology, vol. 139, no. 2, pp. 209–218, 2003.

   View at: Publisher Site | Google Scholar

7. K. H. Kwon, A. Murakami, T. Tanaka, and H. Ohigashi, “Dietary rutin, but not its aglycone quercetin, ameliorates dextran sulfate sodium-induced experimental colitis in mice: attenuation of pro-inflammatory gene expression,” Biochemical Pharmacology, vol. 69, no. 3, pp. 395–406, 2005.

   View at: Publisher Site | Google Scholar

8. S. V. Popov, R. G. Ovodova, P. A. Markov, I. R. Nikitina, and Y. S. Ovodov, “Protective effect of comaruman, a pectin of cinquefoil Comarum palustre L., on acetic acid-induced colitis in mice,” Digestive Diseases and Sciences, vol. 51, no. 9, pp. 1532–1537, 2006.

   View at: Publisher Site | Google Scholar

9. Y.-H. Zhou, J.-P. Yu, Y.-F. Liu et al., “Effects of Ginkgo biloba extract on inflammatory mediators (SOD, MDA, TNF-$a$, NF-$?$Bp65, IL-6) in TNBS-induced colitis in rats,” Mediators of Inflammation, vol. 2006, Article ID 92642, 9 pages, 2006.

   View at: Publisher Site | Google Scholar

10. G. Rogler and T. Andus, “Cytokines in inflammatory bowel disease,” World Journal of Surgery, vol. 22, no. 4, pp. 382–389, 1998.

    View at: Publisher Site | Google Scholar

11. S. Wirtz and M. F. Neurath, “Animal models of intestinal inflammation: new insights into the molecular pathogenesis and immunotherapy of inflammatory bowel disease,” International Journal of Colorectal Disease, vol. 15, no. 3, pp. 144–160, 2000.

    View at: Publisher Site | Google Scholar

12. P. L. Bertevello, A. F. Logullo, S. Nonogaki et al., “Immunohistochemical assessment of mucosal cytokine profile in acetic acid experimental colitis,” Clinics, vol. 60, no. 4, pp. 277–286, 2005.

    View at: Google Scholar

13. D. Raddatz, M. Bockemühl, and G. Ramadori, “Quantitative measurement of cytokine mRNA in inflammatory bowel disease: relation to clinical and endoscopic activity and outcome,” European Journal of Gastroenterology & Hepatology, vol. 17, no. 5, pp. 547–557, 2005.

    View at: Publisher Site | Google Scholar

14. H. M. Alzuherri, C. J. Woodall, and C. J. Clarke, “Increased intestinal TNF-$\alpha$, IL-1$\beta$ and IL-6 expression in ovine paratuberculosis,” Veterinary Immunology and Immunopathology, vol. 49, no. 4, pp. 331–345, 1996.

    View at: Publisher Site | Google Scholar

15. S. Fournout, C. M. Dozois, M. Odin et al., “Lack of a role of cytotoxic necrotizing factor 1 toxin from Escherichia coli in bacterial pathogenicity and host cytokine response in infected germfree piglets,” Infection and Immunity, vol. 68, no. 2, pp. 839–847, 2000.

    View at: Publisher Site | Google Scholar

16. T. Brasseur, “Etudes botaniques, phytochimiques et pharmacologiques consacrées au thym,” Journal de Pharmacie de Belgique, vol. 38, no. 5, pp. 261–272, 1983.

    View at: Google Scholar

17. T. Essawi and M. Srour, “Screening of some Palestinian medicinal plants for antibacterial activity,” Journal of Ethnopharmacology, vol. 70, no. 3, pp. 343–349, 2000.

    View at: Publisher Site | Google Scholar

18. K. Miura, H. Kikuzaki, and N. Nakatani, “Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method,” Journal of Agricultural and Food Chemistry, vol. 50, no. 7, pp. 1845–1851, 2002.

    View at: Publisher Site | Google Scholar

19. K. M. Soliman and R. I. Badeaa, “Effect of oil extracted from some medicinal plants on different mycotoxigenic fungi,” Food and Chemical Toxicology, vol. 40, no. 11, pp. 1669–1675, 2002.

    View at: Publisher Site | Google Scholar

20. M. Hudaib, E. Speroni, A. M. Di Pietra, and V. Cavrini, “GC/MS evaluation of thyme (Thymus vulgaris L.) oil composition and variations during the vegetative cycle,” Journal of Pharmaceutical and Biomedical Analysis, vol. 29, no. 4, pp. 691–700, 2002.

    View at: Publisher Site | Google Scholar

21. P. C. Braga, M. Dal Sasso, M. Culici, T. Bianchi, L. Bordoni, and L. Marabini, “Anti-inflammatory activity of thymol: inhibitory effect on the release of human neutrophil elastase,” Pharmacology, vol. 77, no. 3, pp. 130–136, 2006.

    View at: Publisher Site | Google Scholar

22. Y. Suzuki and H. Furuta, “Stimulation of guinea pig neutrophil superoxide anion-producing system with thymol,” Inflammation, vol. 12, no. 6, pp. 575–584, 1988.

    View at: Publisher Site | Google Scholar

23. R. Aeschbach, J. Löliger, B. C. Scott et al., “Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol,” Food and Chemical Toxicology, vol. 32, no. 1, pp. 31–36, 1994.

    View at: Publisher Site | Google Scholar

24. N. Didry, L. Dubreuil, and M. Pinkas, “Activity of thymol, carvacrol, cinnamaldehyde and eugenol on oral bacteria,” Pharmaceutica Acta Helvetiae, vol. 69, no. 1, pp. 25–28, 1994.

    View at: Publisher Site | Google Scholar

25. M. E. Venturini, D. Blanco, and R. Oria, “In vitro antifungal activity of several antimicrobial compounds against Penicillium expansum,” Journal of Food Protection, vol. 65, no. 5, pp. 834–839, 2002.

    View at: Google Scholar

26. A. Mahmoud, “Antifungal action and anti aflatoxigenic properties of some essential oil constituents,” Letters in Applied Microbiology, vol. 19, pp. 110–113, 1994.

    View at: Google Scholar

27. S. Fujisawa and Y. Kadoma, “Effect of phenolic compounds on the polymerization of methyl methacrylate,” Dental Materials, vol. 8, no. 5, pp. 324–326, 1992.

    View at: Publisher Site | Google Scholar

28. M. H. Alma, A. Mavi, A. Yildirim, M. Digrak, and T. Hirata, “Screening chemical composition and in vitro antioxidant and antimicrobial activities of the essential oils from Origanum syriacum L. growing in Turkey,” Biological & Pharmaceutical Bulletin, vol. 26, no. 12, pp. 1725–1729, 2003.

    View at: Publisher Site | Google Scholar

29. C. C. Arcila-Lozano, G. Loarca-Piña, S. Lecona-Uribe, and E. González De Mejía, “Oregano: properties, composition and biological activity,” Archivos Latinoamericanos de Nutricion, vol. 54, no. 1, pp. 100–111, 2004.

    View at: Google Scholar

30. H. Tian and D. M. Lai, “Analysis on the volatile oil in Origanum vulgare,” Zhongyaocai, vol. 29, no. 9, pp. 920–921, 2006.

    View at: Google Scholar

31. B. Bozin, N. Mimica-Dukic, N. Simin, and G. Anackov, “Characterization of the volatile composition of essential oils of some lamiaceae spices and the antimicrobial and antioxidant activities of the entire oils,” Journal of Agricultural and Food Chemistry, vol. 54, no. 5, pp. 1822–1828, 2006.

    View at: Publisher Site | Google Scholar

32. K. Horošová, D. Bujňáková, and V. Kmet, “Effect of oregano essential oil on chicken Lactobacilli and E. coli,” Folia Microbiologica, vol. 51, no. 4, pp. 278–280, 2006.

    View at: Google Scholar

33. J. L. Wallace, W. K. MacNaughton, G. P. Morris, and P. L. Beck, “Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease,” Gastroenterology, vol. 96, no. 1, pp. 29–36, 1989.

    View at: Google Scholar

34. Š. Juhás, Š. Cikoš, S. Czikková et al., “Effects of borneol and thymoquinone on TNBS induced colitis in mice,” submitted to Folia Biologica.

    View at: Google Scholar

35. J. Vandesompele, K. De Preter, F. Pattyn et al., “Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes,” Genome Biology, vol. 3, no. 7, pp. research0034.1–research0034.11, 2002.

    View at: Publisher Site | Google Scholar

36. M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976.

    View at: Publisher Site | Google Scholar

37. A. A. Parikh, A. L. Salzman, J. E. Fischer, C. Szabó, and P.-O. Hasselgren, “Interleukin-1$\beta$ and interferon-$\gamma$ regulate interleukin-6 production in cultured human intestinal epithelial cells,” Shock, vol. 8, no. 4, pp. 249–255, 1997.

    View at: Google Scholar

38. E. S. Hungness, T. A. Pritts, G.-J. Luo, X. Sun, C. G. Penner, and P.-O. Hasselgren, “The transcription factor activator protein-1 is activated and interleukin-6 production is increased in interleukin-1 $\beta$-stimulated human enterocytes,” Shock, vol. 14, no. 3, pp. 386–391, 2000.

    View at: Google Scholar

39. S. Aydin, A. A. Başaran, and N. Başaran, “Modulating effects of thyme and its major ingredients on oxidative DNA damage in human lymphocytes,” Journal of Agricultural and Food Chemistry, vol. 53, no. 4, pp. 1299–1305, 2005.

    View at: Publisher Site | Google Scholar

40. F. Dušan, S. Marián, D. Katarína, and B. Dobroslava, “Essential oils—their antimicrobial activity against Escherichia coli and effect on intestinal cell viability,” Toxicology in Vitro, vol. 20, no. 8, pp. 1435–1445, 2006.

    View at: Publisher Site | Google Scholar

41. S. Santoyo, S. Cavero, L. Jaime, E. Ibañez, F. J. Señoráns, and G. Reglero, “Supercritical carbon dioxide extraction of compounds with antimicrobial activity from Origanum vulgare L.: determination of optimal extraction parameters,” Journal of Food Protection, vol. 69, no. 2, pp. 369–375, 2006.

    View at: Google Scholar

42. B. Adam, T. Liebregts, J. Best et al., “A combination of peppermint oil and caraway oil attenuates the post-inflammatory visceral hyperalgesia in a rat model,” Scandinavian Journal of Gastroenterology, vol. 41, no. 2, pp. 155–160, 2006.

    View at: Publisher Site | Google Scholar

43. Z. Sun and R. Andersson, “NF-$\kappa$B activation and inhibition: a review,” Shock, vol. 18, no. 2, pp. 99–106, 2002.

    View at: Google Scholar

44. Y. Deguchi, A. Andoh, O. Inatomi et al., “Curcumin prevents the development of dextran sulfate sodium (DSS)-induced experimental colitis,” to apper in Digestive Diseases and Sciences.

    View at: Publisher Site | Google Scholar

45. A. Murakami, K. Matsumoto, K. Koshimizu, and H. Ohigashi, “Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-$\gamma$-induced I$\kappa$B degradation in RAW264.7 macrophages,” Cancer Letters, vol. 195, no. 1, pp. 17–25, 2003.

    View at: Publisher Site | Google Scholar

46. Y. L. Lin, S. H. Tsai, S. Y. Lin-Shiau, C. T. Ho, and J. K. Lin, “Theaflavin-3,$3^{\prime }$-digallate from black tea blocks the nitric oxide synthase by down-regulating the activation of NF-$\kappa$B in macrophages,” European Journal of Pharmacology, vol. 367, no. 2-3, pp. 379–388, 1999.

    View at: Publisher Site | Google Scholar

47. K. Stalińska, A. Guzdek, M. Rokicki, and A. Koj, “Transcription factors as targets of the anti-inflammatory treatment. A cell culture study with extracts from some Mediterranean diet plants,” Journal of Physiology and Pharmacology, vol. 56, supplement 1, pp. 157–169, 2005.

    View at: Google Scholar