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Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France

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Abstract

Endometriosis, defined as estrogen-dependent lesions containing endometrial glands and stroma outside the uterus, is a chronic and often painful gynecological condition that affects 6% to 10% of reproductive age women. Endometriosis has estimated annual costs of US $12 419 per woman (approximately €9579), comprising one-third of the direct health care costs with two-thirds attributed to loss of productivity. Decreased quality of life is the most important predictor of direct health care and total costs. It has been estimated that there is a mean delay of 6.7 years between onset of symptoms and a surgical diagnosis of endometriosis, and each affected woman loses on average 10.8 hours of work weekly, mainly owing to reduced effectiveness while working. To encourage and facilitate research into this debilitating disease, a consensus workshop to define future directions for endometriosis research was held as part of the 11th World Congress on Endometriosis in September 2011 in Montpellier, France. The objective of this workshop was to review and update the endometriosis research priorities consensus statement developed following the 10th World Congress on Endometriosis in 2008.1 A total of 56 recommendations for research have been developed, grouped under 6 subheadings: (1) diagnosis, (2) classification and prognosis, (3) clinical trials, treatment, and outcomes, (4) epidemiology, (5) pathophysiology, and (6) research policy. By producing this consensus international research priorities statement, it is the hope of the workshop participants that researchers will be encouraged to develop new interdisciplinary research proposals that will attract increased funding support for work on endometriosis.

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Authors and Affiliations

  1. Department of Obstetrics & Gynecology, University of Melbourne, Royal Women’s Hospital, Level 7, 20 Flemington Rd, 3052, Parkville, Victoria, Australia

    Peter A. W. Rogers BSc, PhD

  2. Department of Development and Regeneration, Leuven University, Belgium

    Thomas M. D’Hooghe MD, PhD

  3. Department of Obstetrics and Gynecology, Leuven University Hospitals, Belgium

    Thomas M. D’Hooghe MD, PhD

  4. Department of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, MI, USA

    Asgerally Fazleabas PhD

  5. Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, USA

    Linda C. Giudice MD, PhD, MSc

  6. Queensland Institute of Medical Research, Department of Genetics and Computational Biology, Brisbane, Australia

    Grant W. Montgomery PhD

  7. Obstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, Italy

    Felice Petraglia MD

  8. Department of Obstetrics and Gynecology, Wake Forest School of Medicine, Winston-Salem, NC, USA

    Robert N. Taylor MD, PhD

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  1. Peter A. W. Rogers BSc, PhD
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  2. Thomas M. D’Hooghe MD, PhD
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  3. Asgerally Fazleabas PhD
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  4. Linda C. Giudice MD, PhD, MSc
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  5. Grant W. Montgomery PhD
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  6. Felice Petraglia MD
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  7. Robert N. Taylor MD, PhD
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Correspondence to Peter A. W. Rogers BSc, PhD.

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Rogers, P.A.W., D’Hooghe, T.M., Fazleabas, A. et al. Defining Future Directions for Endometriosis Research: Workshop Report From the 2011 World Congress of Endometriosis in Montpellier, France. Reprod. Sci. 20, 483–499 (2013). https://doi.org/10.1177/1933719113477495

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