Journal of Lipid Research
Research ArticleIn vivo MRS assessment of altered fatty acyl unsaturation in liver tumor formation of a TGFα/c-myc transgenic mouse model*
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Abbreviations
CSI, chemical shift imaging
DU, degree of unsaturation
FDR, false discovery rate
FADS1, fatty acid desaturase 1
FADS2, fatty acid desaturase 2
GPCho, glycerol phosphatidylcholine
GPE, glycerol phosphatidylethanolamine
HCC, hepatocellular carcinoma
MRS, magnetic resonance spectroscopy
PC, phosphatidylcholine
PE, phosphatidylethanolamine
PI, precursor ion
ROI, region of interest
SCD, stearoyl CoA desaturase
TE, echo time
TR, relaxation time
Published, JLR Papers in Press, December 8, 2008.
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Support for the studies was provided by funding from the Oklahoma Medical Research, the Oklahoma Center for the Advancement of Sciences and Technology (OCAST), grant of fMRI-2, Molecular Image Inc. (Menlo Park, CA), and National Institutes of Health grant RO1CA82506.