ABSTRACT

Adoptive transfer experiments have been used to clarify many aspects of the immune system regulation. But Rob Loblay and Tony Basten here describe a very nasty (or should we say “elegant”?) paradox concerning suppression in adoptive transfer experiments, that should be resolved before we can confidently interpret adoptive transfer experiments. Might the Loblay-Basten paradox be related to the isogeneic barrier, discussed in Chapter 20 by Sikora and Levy?