ABSTRACT
Nanotechnology has shown promise in biomedical applications for diagnosis and treatment purposes. This chapter describes the synthesis of different metal nanoparticles using microfluidic devices and their potential biomedical applications, such as sensing, imaging, and therapeutics and diagnostics. Multiphase microfluidics is complex compared to single-phase microfluidics. Its design and function include interaction among various physiochemical phenomena, such as chemical reactions, heat and mass transport, and the hydrodynamics of fluid and the surface phenomenon. Continuous- (laminar) and segmented-flow types of microfluidic processes have been used to synthesize metallic nanoparticles, with their unique physical and chemical characteristics and controlled nano-structure. Biosensing is an important tool for early detection and sensing of medical parameters for healthcare applications. Optical properties of metallic nanoparticles provide many opportunities in biosensing. The chapter also elaborates the future challenges of nanoparticle preparation using microfluidic devices and their applications, advantages, and limitations.
