ABSTRACT
Body uid homeostasis and arterial pressure are intimately related to the point that their control share many common mechanisms. The diagram shown in Figure 4.1 illustrates an interactive network (antidehydration network) activated by the dehydration of the two major body uid compartments, extracellular [represented by the production of angiotensin II (ANG II)] and intracellular (represented by hyperosmolarity). The operation of the network involves redundancy and reciprocity and results in effector mechanisms that counteract dehydration. Although highly simpli-ed (many important factors, e.g., aldosterone, are omitted), the network diagram
4.1 Introduction .................................................................................................... 67 4.2 Electrolytic Lesions of AV3V: General Effects on Control of Body
Fluid Homeostasis .......................................................................................... 71 4.3 AV3V Region: Control of Salivary Gland Function and Thermoregulation ..... 73 4.4 Importance of AV3V Region for Recovery from Hemorrhage ...................... 74 4.5 Importance of AV3V for Cardiovascular Responses to Activation of
Hindbrain Areas ............................................................................................. 75 4.5.1 Short-Term Control ............................................................................. 76 4.5.2 Long-Term Control: Hypertension ...................................................... 78
4.6 AV3V Lesion: Brain Plasticity and Resilience ...............................................80 4.7 Conclusions ..................................................................................................... 81 References ................................................................................................................ 82
suggests complex control systems orchestrated by the brain. When deranged, the operation of such systems may lead to pathologies, for example, hypertension.
